Valcyte 450 mg

Generic Name: Valganciclovir 450 mg
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Best Value On Brand Valcyte 450 mg
Price: $42.61 per tab!
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60 tabs for $2,556.43 ($42.61 per tab)
Valcyte from online pharmacy: Canada
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Best Value On Generic Valganciclovir 450 mg
Price: $10.49 per tab!
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Our licensed online pharmacy offers Valcyte 450 mg for sale. Enhance your life and manage your viral with medications like Valcyte 450 mg. Your doctor should be consulted before taking any new medication. It is possible, in some cases, to obtain a generic version of a particular medication; e.g. a generic substitute for Valcyte 450 mg. The generic is therapeutically equivalent and often costs less, which means you can save money when buying your rx online from The Drug Company.

About Valcyte

What Valcyte is used for

  • VALCYTE is a prescription medication that belongs to the family of drugs known as “antivirals”

  • VALCYTE is used to treat cytomegalovirus (CMV) retinitis in people who have acquired immunodeficiency syndrome (AIDS).

  • VALCYTE is also used to prevent cytomegalovirus (CMV) disease in people who have received a solid organ transplant and are at risk of developing CMV disease.

What Valcyte does

  • VALCYTE works by slowing the growth of CMV virus, the virus that causes CMV retinitis as well as infection at other sites in the body. For most people with CMV retinitis, VALCYTE prevents CMV from progressing (spreading) into healthy cells as quickly as it would without treatment, thereby protecting eyesight from damage due to CMV disease.

  • VALCYTE does not cure CMV retinitis, and some people may experience progression of retinitis during or following treatment with VALCYTE. Therefore, you must follow your doctor’s advice and have your eyes checked regularly.

  • For most patients who have received a solid organ transplant, VALCYTE prevents the occurrence of CMV disease up to 6 months after the transplant.

  • VALCYTE is a prodrug of ganciclovir. This means it is changed to ganciclovir once it is absorbed into the body. Ganciclovir is the active part of the drug that actually slows the growth of CMV virus.

When Valcyte should not be used

Do not take VALCYTE if you have ever had a serious reaction to valganciclovir, ganciclovir (as VALCYTE or ganciclovir capsules or CYTOVENE-IV). Do not take if you have had sensitivity reactions with acyclovir, ganciclovir and valacyclovir as a similar reaction can occur with VALCYTE. Do not take VALCYTE if you have any reaction to any of the nonmedicinal ingredients (see What the nonmedicinal ingredients are:).

What the medicinal ingredient is

The medicinal ingredient found in VALCYTE is valganciclovir hydrochloride.

What the nonmedicinal ingredients for Valcyte are

VALCYTE tablets contain the following nonmedicinal ingredients: crospovidone, microcrystalline cellulose, povidone K-30, and stearic acid powder. The film-coat applied to the tablets is Opadry Pink, which contains hydroxypropyl methylcellulose, polyethylene glycol 400/macrogol, polysorbate 80, synthetic red iron oxide, and titanium dioxide.

What dosage forms Valcyte comes in

VALCYTE is available as a pink 450 mg valganciclovir film-coated tablet (as valganciclovir hydrochloride).

VALCYTE is also available as a powder for oral solution. The solution will be prepared by your pharmacist and will be a fruit-flavoured liquid containing 50mg/ml valganciclovir (as valganciclovir hydrochloride).


Warnings and Precautions

BEFORE you use VALCYTE talk to your doctor or pharmacist if:

  • you have ever had a bad reaction to VALCYTE (valganciclovir) or any of the inactive ingredients shown above.

  • you have ever had a bad reaction to ganciclovir, acyclovir or valacyclovir.

  • you are allergic to other medicines, food and dyes.

  • you are taking ANY other medicines (prescription or nonprescription) including herbal or natural products.

  • you have any other illnesses/diseases, including a history of liver or kidney disease.

  • you are receiving hemodialysis as dosage adjustment is required.

  • you have blood problems

  • you or your partner are pregnant, plan on becoming pregnant, or are breast-feeding a child, as VALCYTE may cause birth defects in humans and should not be used during pregnancy. If there is any chance that you or your partner could become pregnant, it is very important for you to use effective contraception during and for at least 90 days following treatment with VALCYTE. For women this means using barrier protection (condoms) and one additional form of contraception (birth control pills, intrauterine device). For men this means using barrier protection (condoms). Women who are HIV positive should not breast feed because HIV infection can be passed to the baby via the breast milk.

This information will help your doctor and you decide whether you should use VALCYTE and what extra care may need to be taken while you are on the medication. You should always consult your doctor or pharmacist before using other medications while on VALCYTE.


Interactions with Valcyte

Tell your doctor or pharmacist about all medications that you are taking, including those you buy over the counter and herbal or natural products. VALCYTE may change the effect of other medications.

The following drugs may need to have their dose changed when taken with VALCYTE:

  • Videx (didanosine, ddI)

  • Retrovir (zidovudine, ZDV, AZT)

  • Benuryl (probenecid)

Talk to your doctor if you are taking imipenem-cilastin. Convulsions have occurred in patients taking imipenem-cilastin and ganciclovir. You may discuss different options with your doctor.


Proper Use of Valcyte

Dosing Considerations

  • Your doctor has prescribed VALCYTE after carefully studying your case. Other people may not benefit from taking this medicine, even though their problems may seem similar to yours. Do not give your VALCYTE to anyone else.

  • To make sure that your therapy is as effective as possible, take your VALCYTE exactly as your doctor prescribes it. Do not skip any doses, or take more than the recommended dose.

  • Take VALCYTE with food.

  • Do not break or crush VALCYTE tablets. Avoid contact with broken VALCYTE tablets on your skin, mucous membranes or eyes. If contact occurs, wash your skin well with soap and water or rinse your eyes well with sterile or plain water if sterile water is not available.

Usual dose

Treatment of CMV Retinitis in Patients with AIDS

  • The usual dosage for adults to get active CMV retinitis under control (induction therapy) is two 450 mg tablets twice a day for 21 days.

  • The usual dosage for adults to help keep CMV retinitis under control (maintenance therapy) is two 450 mg tablets once a day.

Prevention of CMV Disease Solid Organ Transplantation

  • The usual dosage to prevent CMV in adults who received a solid organ transplant is two 450 mg tablets once a day starting within 10 days of transplant and continuing until 100 days after the transplant.

Overdose

In cases of overdose or suspected overdose, contact the poison control centre or your physician immediately.

Missed dose

  • If you forget to take a dose of VALCYTE take it as soon as possible, then just carry on with the regular times you take your medication. If you remember your missed dose close to the time for your next dose, do not take the missed dose. Two doses of VALCYTE should not be taken at the same time.

  • Do not let your VALCYTE run out. The amount of virus in your blood may increase if your medicine is stopped, even for a short time.

  • It may be a good idea to ask your doctor or pharmacist ahead of time what to do about missed doses.


Side Effects for Valcyte and What to Do About Them

Unwanted effects are possible with all medicines. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking VALCYTE.

Blood problems

VALCYTE can cause serious blood cell problems. These include reduced numbers of certain white blood cells (granulocytopenia, neutropenia, or leukopenia), reduced numbers of red blood cells (anemia), and reduced numbers of platelets (thrombocytopenia). VALCYTE may also cause blood creatinine elevation, increased potassium in the blood, and abnormal liver function. Your doctor should recommend that you have blood tests done on a regular basis.

Kidney problems

VALCYTE can cause an increase in serum creatinine (an indicator of kidney function). An increase in serum creatinine may indicate abnormal kidney function. Your doctor may have blood tests done on a regular basis to monitor your serum creatinine.

Technical Information