Nexium

Nexium Medication Information:

Price Break On Nexium
Generic is available for less money: Generic Esomeprazole

Nexium medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Nexium 20 mg
Nexium 40 mg

Nexium Information

Nexium (esomeprazole magnesium) is an orally taken pill coated with a time release material that lowers stomach acid to relief many symptoms, pain, and damage such as heart burn and erosive diseases caused by this excesive amount of acid. It is in a class of medications called proton pump inhibitors (PPIs).

What is it for?

Nexium is widely used to treat the damaging effects of excess stomach acid. Disorders recomended for treatment with this medication is gastroesophageal reflux disease (GERD), erosive esophagitis (EE), and other acidic induced complications such as heartburn.

How to use Nexium?

How much to take, when to take and why it is prescribed of course varies for each individual. However, the average dose usually ranges from a 20mg to 40mg capsule taken an hour before a meal each day when treated for common problems regarding excessive stomach acid. It is prescribed to fix or regulate a reocuring problem which is why it is recommended to take for only a couple weeks to around two months. It was not intended to be a medication to be taken for long term regiments.

Side Effects:

Side effects also vary and cannot be anticipated. The most common are constipation, headaches, diarrhea, fatigue, gas, and nausea. Infrequently, nervousness, abnormal heartbeat, muscle pain, weakness, leg cramps and water retention can happen as well. It is more likely that an allergic reaction could occur when mixed with a certain food, drink, or other medication.

Other Brand Names:

Esomeprazole is the generic name, but their are no generic versions made at the moment. This is because the patent period on Nexium has not expired yet. When it does, other manufactures will start making Nexium with a decreased selling price. Nexium is quite expensive, so some people take an over the counter medication known as Prilosec which is very similar and effective in it, therefore making it an inexpensive alternative.

Safety Information:

People who are allergic to esomeprazole or to any other benzimidazole medication such as albendazole (Albenza), or mebendazole (Vermox) shouldn't take Nexium. Also those who have ever had liver disease or any type of heart disease may be risking their health and may need a dose adjustment or special tests during treatment.

Dosage:

  • 10mg- children under 11
  • 20mg- low adult dose
  • 40mg- high adult dose

Visual Description:

The capsule is opaque, made of hard-gelatin,and an amethyst-colored capsules with three yellow bars on the cap.

About NEXIUM

What Nexium is used for

In adults, NEXIUM is used for the treatment of acid-related disorders such as:

  • reflux esophagitis (tissue damage caused by stomach content flowing back up the food pipe) and symptoms of gastroesophageal reflux disease (GERD) in patients with reflux esophagitis

  • duodenal ulcers caused by infection with a bacterium called H. pylori in combination with other antibiotics, and to help reduce the risk of these ulcers from coming back

  • the symptoms of nonerosive reflux disease (NERD), which are not related to tissue damage within the food pipe, such as: a burning feeling rising from the chest towards the neck (heartburn) and the flow of bitter/sour juice into the mouth (regurgitation)

  • rare pathological hypersecretory conditions, including “Zollinger-Ellison syndrome”, which cause the stomach to produce large amounts of acid.

NEXIUM is also used to heal and/or reduce the risk of ulcers that can be caused by medication you may be taking for pain or joint problems such as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) or acetylsalicylic acid (i.e. Aspirin).

In children (1-17 years of age), NEXIUM is used for the treatment of acid-related disorders such as:

  • reflux esophagitis (tissue damage caused by stomach content flowing back up the food pipe) and symptoms of gastroesophageal reflux disease (GERD) in patients with reflux esophagitis

  • the symptoms of nonerosive reflux disease (NERD), which are not related to tissue damage within the food pipe, such as: a burning feeling rising from the chest towards the neck (heartburn) and the flow of bitter/sour juice into the mouth (regurgitation).

What Nexium does

NEXIUM works by causing less acid to be made in your stomach.

When Nexium should not be used

If you are allergic to the active ingredient esomeprazole or any of the other ingredients of NEXIUM (see What the important nonmedicinal ingredients are:). If you think you may be allergic, ask your doctor for advice.

What the medicinal ingredient is

NEXIUM contains esomeprazole magnesium trihydrate as the active ingredient.

What the important nonmedicinal ingredients for Nexium are

Each NEXIUM tablet contains the following nonmedicinal ingredients (listed in alphabetical order): cellulose microcrystalline, crospovidone, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, iron oxide, magnesium stearate, methacrylic acid ethylacrylate copolymer, polyethylene glycol, polysorbate, synthetic paraffin, sodium stearyl fumarate, sugar spheres, talc, titanium dioxide, triethyl citrate.

NEXIUM granules for oral suspension contain the following nonmedicinal ingredients (listed in alphabetical order): citric acid, crospovidone, dextrose, glycerol monostearate, hydroxypropyl cellulose, hypromellose, iron oxide, magnesium stearate, methacrylic acid copolymer type C, polysorbate, sugar spheres, talc, triethyl citrate, xanthan gum.

Check with your doctor or pharmacist if you think you may be allergic to any of the above ingredients.

What dosage forms Nexium comes in

NEXIUM 20 mg tablets come in blister packages that contain 30 tablets. NEXIUM 40 mg tablets come in blister packages that contain 30 or 60 tablets, or bottles that contain 100 tablets.

NEXIUM 10 mg granules for oral suspension come in unit dose sachets in cartons of 30.


Warnings and Precautions

BEFORE or DURING your use of NEXIUM talk to your doctor or pharmacist about:

  • symptoms that may be a sign of a more serious problem in your stomach or intestine such as: trouble swallowing, unplanned weight loss, vomiting blood or food, or black (blood-stained) stools

  • if you are pregnant or trying to become pregnant

  • if you are allergic to esomeprazole or any other ingredients or components of the container

  • if you have health problems now or have had any in the past

  • other medications you take, including ones you can buy without a prescription


Interactions with NEXIUM

Blood levels of some drugs may be influenced if NEXIUM is taken at the same time as drugs used to prevent fungal infections (itraconazole, ketoconazole, voriconazole), anxiety (diazepam), epilepsy (phenytoin) and drugs to speed up stomach emptying (cisapride{*No longer marketed in Canada.}). However, none of these interactions have been shown to change the effectiveness of NEXIUM or the other drug.

Drugs used for blood clotting (warfarin or coumarin derivatives) have been reported to interact with NEXIUM. Speak to your doctor or pharmacist if you are taking any of these drugs.

NEXIUM may decrease the effectiveness of some drugs used for HIV treatment (atazanavir and nelfinavir).

During episodic dosing of NEXIUM when needed, your response to potential drug interactions may change as compared to daily dosing during the entire, initial treatment period.

Please inform your doctor or pharmacist if you are taking or have recently taken any other medicines.


Proper Use of NEXIUM

Administration

NEXIUM may be taken with food or on an empty stomach.

Tablets

The tablet may be swallowed whole with water. It may also be put in half a glass of water where it will break apart. This will make it easier to swallow. Be sure to swallow all the tiny pellets that come out of the tablet without chewing them. Don’t let the pellets sit in water for more than 30 minutes before drinking them. After drinking, rinse the glass with water and drink this as well.

Granules for oral suspension

Empty the contents of each sachet into a container containing 1 tablespoon (15 mL) of water. Stir. Leave for a few minutes to thicken. The mixture will appear as a thick yellow suspension with small white and/or brownish granules. Stir again and drink within 30 minutes. If any material remains after drinking, add more water, stir, and drink right away.

Usual dose

Adults

Take all doses of NEXIUM as directed by your doctor. Do so even when you feel well. In some cases, daily doses are needed to control your pain and symptoms and to help damaged areas heal. The suggested dose for treating acute disease is 20 to 40 mg once a day for 2 to 8 weeks. Your doctor may suggest that you continue taking NEXIUM 20 mg each day. This is to keep your symptoms from coming back.

Follow the directions given to you by your doctor. They may differ from the information contained in this leaflet.

NEXIUM may be used together with antibiotic drugs for one week to treat ulcers caused by H. pylori. This also helps to reduce the risk of these ulcers from coming back. Your prescription may say NEXIUM 1-2-3 A. This tells the pharmacist to give you three different drugs (NEXIUM and two antibiotics). The pharmacist should also give you information on the two antibiotics that will be used in combination with NEXIUM.

If you receive NEXIUM plus antibiotic drugs, take all three drugs twice each day. Do so at the correct time each day for one week. This will ensure they work properly. Studies have shown that patients who take their drugs as prescribed, have better ulcer healing rates and greater success getting rid of their H. pylori infection.

It is important to take NEXIUM until your doctor tells you to stop. This is true even if you start to feel better in a few days. NEXIUM needs to be taken for the full treatment duration to help correct acid problems.

Maintenance treatment of NERD (on-demand) dose

After initial treatment of NERD, your doctor may suggest that you take NEXIUM 20 mg once daily, as needed, if symptoms of heartburn and regurgitation return periodically. Contact your doctor if your symptoms get worse, persist or if new symptoms arise.

Children (1-17 years of age)

Take all doses of NEXIUM as directed by your doctor. Do so even when you/your child feels well. NEXIUM needs to be taken for the full treatment duration to help correct acid problems.

Follow the directions given to you by your doctor. They may differ from the information contained in this leaflet.

Children (1-11 years of age)

The suggested dose for treating acute disease is 10 mg (1 sachet) or 20 mg (2 sachets) once daily for 8 weeks.

Children (12-17 years of age)

The suggested dose for treating acute disease is 20 or 40 mg once a day for 2 to 8 weeks.

Nexium Facts

AstraZeneca, the maker of Nexium, employs over 65,000 people in more than 100 countries.

AstraZeneca invested more than $5 billion in research and development in 2008.

Sales of Nexium netted more than $3 billion in 2003.

The Purple Pill is a trademark of AstraZeneca, the maker of Nexium.

 

Technical Information

What Others Are Saying About nexium:

Kyle Busey on Tuesday November 18, 2008

Living and dealing with a stomach ulcer is no fun. I'm not sure of the cause, but my remedy, in part, is Nexium. Thanks for your kind mannerismn on the phone, and your reliable service. Oh, and home delivery is wonderful!

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