Sutent 50 mg

 
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Best Value On Brand Sutent 50 mg
Price: $320.35 per tab!
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Sutent 50 mg Prescription Required
28 tabs for $8,969.81 ($320.35 per tab)
Sutent from online pharmacy: South Africa
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Our licensed online pharmacy offers Sutent 50 mg for sale. Enhance your life and manage your with medications like Sutent 50 mg. Your doctor should be consulted before taking any new medication. It is possible, in some cases, to obtain a generic version of a particular medication; e.g. a generic substitute for Sutent 50 mg. The generic is therapeutically equivalent and often costs less, which means you can save money when buying your rx online from The Drug Company.

About Sutent

What Sutent is used for

SUTENT is an oral medicinal product used in the treatment of malignant GIST, a cancer of the stomach and bowels. GIST arises from uncontrolled cell growth of the supporting tissues of these organs.

SUTENT is also used in the treatment of kidney cancer that has spread to other parts of your body.

What Sutent does

SUTENT specifically targets the activity of certain enzymes called tyrosine kinases that play a major role in transmitting the chemical signals required for critical cellular processes. SUTENT prevents the growth of blood vessels from surrounding tissue to a solid tumour, and prevents the proliferation of cancer cells.

When Sutent should not be used

Do not take SUTENT:

  • If you are allergic (hypersensitive) to sunitinib or any of the other ingredients of SUTENT, listed under “What the important nonmedicinal ingredients are:”.

  • If you are pregnant.

What the medicinal ingredient is

The active ingredient is sunitinib (as malate salt).

What the important nonmedicinal ingredients for Sutent are

The nonmedicinal ingredients are croscarmellose sodium, magnesium stearate, mannitol and povidone.

The orange capsule shells contain gelatin, red iron oxide and titanium dioxide. The caramel capsule shells also contain black iron oxide and yellow iron oxide. The imprinting ink contains povidone, propylene glycol, shellac, sodium hydroxide and titanium dioxide.

The yellow capsule shells contain titanium dioxide, yellow iron oxide, and gelatin. The imprinting ink for the yellow shells contains shellac, dehydrated alcohol, isopropyl alcohol, butyl alcohol, propylene glycol, strong ammonia solution, potassium hydroxide, and black iron oxide.

What dosage forms Sutent comes in

SUTENT is available as hard gelatin capsules containing 12.5 mg; 25 mg; 37.5 mg; or 50 mg of sunitinib. SUTENT is available in bottles of 28 capsules.

SUTENT 12.5 mg capsules: Capsules are supplied with orange cap and orange body, printed with white ink “Pfizer” on the cap, “STN 12.5 mg” on the body.

SUTENT 25 mg capsules: Capsules are supplied with caramel cap and orange body, printed with white ink “Pfizer” on the cap, “STN 25 mg” on the body.

SUTENT 37.5 mg capsules: Capsules are supplied with standard yellow cap and standard yellow body, printed with black ink “Pfizer” on the cap, “STN 37.5 mg” on the body.

SUTENT 50 mg capsules: Capsules are supplied with caramel cap and caramel body, printed with white ink “Pfizer” on the cap, “STN 50 mg” on the body.


Warnings and Precautions

  • Patients receiving SUTENT should be monitored by a doctor with experience in cancer medicines.

  • Rare cases of Tumour Bleeding have been observed.

  • Decreases in the amount of blood pumped by your heart have been observed.

  • Patients should be monitored for high blood pressure.

  • SUTENT has not been studied in patients with severe kidney or severe liver problems.

  • Rare cases of muscle toxicity have been reported.

SUTENT has an effect on the electrical activity of the heart. This effect can be measured as a change in the electrocardiogram (ECG). This effect can lead to heart rhythm disturbances. These heart rhythm disturbances may be more likely in patients with risk factors, such as heart disease, or in the presence of certain interacting drugs. If you feel dizzy, weak, faint, or light-headed, and your pulse is irregular or unusually low or high, you should stop taking SUTENT and seek immediate medical attention. It is important to follow the instructions of your doctor with regard to dosing or any special tests.

SUTENT may reduce the volume of blood pumped by the heart and your doctor may monitor your condition if you have heart problems.

You may develop blood clots in your legs during SUTENT treatment that could spread to your lungs. Notify your doctor if you develop pain, swelling, or redness in your legs, or if you experience chest pain and shortness of breath, and seek immediate medical attention.

SUTENT may cause your adrenal gland to function improperly and your doctor may monitor your adrenal gland condition especially if you have experienced stress such as surgery, injury or severe infection.

Use of SUTENT may cause changes in your blood and your doctor may have blood tests done before and during treatment.

SUTENT may cause a decrease in your thyroid hormone levels and your doctor may have blood tests done to monitor your thyroid function.

You may develop muscle aches or weakness, or dark-colored urine during SUTENT treatment and your doctor may have blood and urine tests done to evaluate the possibility of muscle toxicity.

Tell your doctor before taking SUTENT, if any of the following apply to you now or even in the past

  • If you have or had liver or kidney problems.

  • If you have high blood pressure.

  • If you are pregnant or think you may be. SUTENT is not to be used during pregnancy. Women who might get pregnant must use effective contraception during treatment with SUTENT.

  • If you are breast-feeding.

  • If you have had recent surgery, injury or a severe infection.

  • If you have a heart condition.

  • If you have had a stroke.

  • If you have a history of fainting spells.

  • If you have a family history of sudden cardiac death at age less than 50 years.

Use in children

Experience with SUTENT in children is insufficient for any recommendations regarding its use to be made.

Male contraception

Male patients should be surgically sterile or agree to use effective contraception during the period of therapy with SUTENT. SUTENT may cause effects on the unborn child should the female partner of a male taking SUTENT become pregnant as the drug may be present in the semen.

Driving and using machines

If you experience (feel) dizziness, do not drive or use machinery.


Interactions with Sutent

Taking other medicines

Tell your doctor if you are taking other drugs, including non-prescription and natural health products, because they may speed up or slow down the breakdown of SUTENT. This may lead to an increase in SUTENT drug levels, which may lead to an increase in the side effects of SUTENT. For example:

  • Antifungals (such as ketoconazole, fluconazole)

  • Calcium channel blockers (such as diltiazem, verapamil)

  • Macrolide antibiotics (such as erythromycin, clarithromycin)

  • Fluoroquinolone antibiotics (such as ciprofloxacin, norfloxacin)

  • Some antivirals (such as ritonavir, indinavir)

  • Herbal medicines (such as St. John’s Wort)

Also, the following list includes some, but not all, of the drugs that may interact with SUTENT to affect the electrical activity of your heart:

  • Antiarrhythmics (drugs that stabilize the heart rhythm function, such as procainamide, quinidine, amiodarone, sotalol, etc.)

  • Antidepressants (mood disorder drugs)

  • Antipsychotics (drugs to stabilize thinking and behaviour)

  • Anti-asthmatics (salmeterol)

  • Opioids (e.g. methadone)

  • Antinauseants (e.g. granisetron, dolasetron, ondansetron)


Proper Use of Sutent

Usual SUTENT Adult dose

Your doctor will prescribe a dose that is right for you. It is recommended that SUTENT be taken orally, once daily for 28 days, followed by 14 days off (no medicine) given as a 42-day (6 weeks) cycle.

Your doctor will determine how many cycles of treatment you will need.

SUTENT can be taken with or without food however it should not be taken with grapefruit juice.

Overdose

If you think you may have taken accidentally too many SUTENT capsules, talk to your doctor immediately. You may require medical attention.

Missed dose

Do not take a double dose to make up for a forgotten dose.


Technical Information