Sensipar Medication Information:

Sensipar medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Sensipar 30 mg
Sensipar 90 mg

About Sensipar

What Sensipar is used for

SENSIPAR is used:

  • to treat secondary hyperparathyroidism (high-per-pear-uh-THIGH-royd-izm) in patients with chronic kidney disease (CKD) receiving dialysis;

  • to reduce high levels of calcium in the blood (hypercalcemia) in patients with parathyroid cancer;

  • to reduce high levels of calcium in the blood (hypercalcemia) in patients with primary hyperparathyroidism when removal of the gland(s) is not possible.

What Sensipar does

Four small glands located behind the thyroid gland in your neck are called parathyroid glands. They make a hormone called parathyroid hormone (PTH). Normally, PTH makes sure you have just enough calcium and phosphorus in your blood to keep your bones, heart, muscles, nerves and blood vessels working well.

Secondary hyperparathyroidism

When your kidneys are working, PTH keeps your calcium and phosphorus levels normal by moving the right amounts of calcium and phosphorus in and out of your bones. Chronic Kidney Disease (CKD) can cause a condition called secondary hyperparathyroidism.

When your kidneys aren’t working properly, the calcium and phosphorus balance in your body is upset, and your parathyroid glands send out too much PTH to your body. This can cause bone disease and also may be a risk factor for heart disease and abnormal calcification of blood vessels and other parts of the body. SENSIPAR treats secondary hyperparathyroidism by lowering PTH. This helps keep calcium and phosphorus within proper levels.

Parathyroid carcinoma/Primary hyperparathyroidism

Primary hyperparathyroidism is caused by an overactive, enlarged parathyroid gland (or glands), occasionally due to cancer of the parathyroid gland. In primary hyperparathyroidism, your parathyroid glands send out too much PTH to your body and your blood level of calcium becomes high. SENSIPAR lowers PTH by telling your parathyroid glands to stop releasing too much PTH into your blood. This helps lower your blood calcium levels.

When Sensipar should not be used

You should not take SENSIPAR if you are hypersensitive (allergic) to any of the ingredients in the tablet.

What the medicinal ingredient is

Cinacalcet hydrochloride.

What the important nonmedicinal ingredients for Sensipar are

Pre-gelatinized starch, microcrystalline cellulose, povidone, crospovidone, colloidal silicon dioxide, magnesium stearate, Opadry II green, clear film-coat (Opadry clear), carnauba wax, and Opacode black ink.

What dosage forms Sensipar comes in

SENSIPAR is available as small, green tablets packaged in bottles of 30 tablets. Each tablet contains 30 mg, 60 mg, or 90 mg of cinacalcet hydrochloride.

Warnings and Precautions

BEFORE you use SENSIPAR talk to your doctor or pharmacist if:

  1. You have or had seizures. The risk of having a seizure is greater if you have had seizures before.

  2. You have or had heart problems (low blood pressure or worsening heart failure).

  3. You have or had liver problems.

  4. You have lower blood calcium levels.

  5. You are pregnant, breastfeeding, or plan to do so.

SENSIPAR is not recommended for patients with CKD not receiving dialysis.

SENSIPAR should not be used in children.

Interactions with Sensipar

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed.

Drugs that may interact with SENSIPAR include: ketoconazole, erythromycin, itraconazole, metoprolol, flecainide, vinblastine, thioridazine, rifampin, phenytoin, or medicines such as tricyclic antidepressants (desipramine, amitriptyline).

Proper Use of Sensipar

It is important to take SENSIPAR exactly as your doctor has instructed you. Your doctor will tell you how much SENSIPAR to take. Your doctor will order regular blood tests to measure how you are responding to SENSIPAR and may increase or decrease your dose based on your PTH, calcium, and phosphate levels.

Usual adult dose

If you have secondary hyperparathyroidism the usual starting dose for SENSIPAR is one 30 mg tablet once daily.

If you have parathyroid cancer or primary hyperparathyroidism, the usual starting dose for SENSIPARis one 30 mg tablet twice daily.

SENSIPAR is taken once a day with food or right after a meal. SENSIPAR tablets must be taken whole and are not to be divided. It’s best to take SENSIPAR at the same time each day.


Tell your doctor or contact your regional Poison Control Centre immediately if you think you took more than the recommended dose of SENSIPAR.

Missed dose

Do not take a double dose to make up for forgotten daily doses. If you have forgotten a dose of SENSIPAR, you should take your next daily dose as normal.

Side Effects for Sensipar and What to Do About Them

All medicines have side effects.

If you have any of the following side effects while taking SENSIPAR, you should tell your doctor right away.

  • Nausea and vomiting. These are the most common side effects seen with SENSIPAR treatment. This may make it difficult to take your medicines.

  • Diarrhea and muscle pain. These side effects also are commonly reported.

  • Rash or hypersensitivity (allergic reactions). Cases of rash have been commonly reported, while cases of hypersensitivity (allergic reactions) have been uncommonly reported.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Diarrhea    
Hypocalcemia/low calcium level (symptoms include: numbness/tingling around mouth, muscle aches/cramps, seizures)    
Uncommon Seizures  
Hypersensitivity (allergic reactions)  
Very Rare Low blood pressure or worsening heart failure  

This is not a complete list of side effects. For any unexpected effects while taking SENSIPAR, contact your doctor or pharmacist.


Technical Information