Kaletra 200mg/50mg

 
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Best Value On Brand Kaletra 200mg/50mg
Price: $4.62 per capsule!
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180 capsules for $831.29 ($4.62 per capsule)
Kaletra from online pharmacy: South Africa
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Our licensed online pharmacy offers Kaletra 200mg/50mg for sale. Enhance your life and manage your with medications like Kaletra 200mg/50mg. Your doctor should be consulted before taking any new medication. It is possible, in some cases, to obtain a generic version of a particular medication; e.g. a generic substitute for Kaletra 200mg/50mg. The generic is therapeutically equivalent and often costs less, which means you can save money when buying your rx online from The Drug Company.

About Kaletra

What Kaletra is used for

KALETRA is for adults and children 6 months of age or older who are infected with the human immunodeficiency virus (HIV), the virus which causes AIDS.

KALETRA is prescribed for use in combination with other antiretroviral medicines.

What Kaletra does

KALETRA is an inhibitor of the HIV protease enzyme. It helps control HIV infection by inhibiting or interfering with the protease enzyme that HIV needs to multiply.

KALETRA is not a cure for HIV infection or AIDS. People taking KALETRA may still develop infections or other serious illnesses associated with HIV disease and AIDS.

When Kaletra should not be used

Do not take KALETRA if you/your child:

  • are allergic to lopinavir, ritonavir or to any of the non-medicinal ingredients in KALETRA. (Refer to “What the important nonmedicinal ingredients are:” for a complete listing).

  • are currently taking any of the following medicines, because they can cause serious problems or death if taken with KALETRA:

    • dihydroergotamine, ergonovine, ergotamine, and methylergonovine (used to treat headaches), such as Cafergot, Migranal, D.H.E. 45, Ergotrate Maleate, Methergine, and others;

    • Halcion (triazolam)—used to relieve anxiety and/or trouble sleeping;

    • Hismanal (astemizole){*Products no longer marketed in Canada.};

    • Orap (pimozide)—used to treat schizophrenia;

    • Propulsid (cisapride)*—used to relieve certain stomach problems;

    • Seldane (terfenadine)*;

    • Versed (midazolam);

  • Do not take KALETRA with rifampin, also known as Rimactane, Rifadin, Rifater, or Rifamate. Rifampin may lower the amount of KALETRA in your blood and make it less effective.

  • Do not take KALETRA with St. John's wort (Hypericum perforatum), a herbal product sold as a dietary supplement, or products containing St. John's wort. Talk with your doctor if you are taking or planning to take St. John's wort. Taking St. John's wort may decrease KALETRA levels and lead to increased viral load and possible resistance to KALETRA or cross-resistance to other anti-HIV medicines.

  • Do not take KALETRA with the cholesterol-lowering medicines Mevacor (lovastatin) or Zocor (simvastatin) because of possible serious reactions. There is also an increased risk of drug interactions between KALETRA and Lipitor (atorvastatin); talk to your doctor before you take any of these cholesterol-reducing medicines with KALETRA.

    • are currently taking any of these medications; your doctor may switch your medication.

What the medicinal ingredients for Kaletra are

Lopinavir and ritonavir.

What the important nonmedicinal ingredients for Kaletra are

KALETRA 100/25 mg tablets also contain copovidone, sorbitan monolaurate, colloidal silicon dioxide, sodium stearyl fumarate, polyvinyl alcohol, titanium dioxide, talc, polyethylene glycol 3350, yellow ferric oxide E172.

KALETRA 200/50 mg tablets also contain copovidone, sorbitan monolaurate, sodium stearyl fumarate, hypromellose, titanium dioxide, polyethylene glycol 400, hydroxypropyl cellulose, talc, colloidal silicon dioxide, polyethylene glycol 3350, yellow ferric oxide E172, and polysorbate 80.

KALETRA oral solution also contains acesulfame potassium, alcohol, artificial cotton candy flavour, natural and artificial vanilla flavour, citric acid, glycerin, Magnasweet-110 flavour, high fructose corn syrup, menthol, polyoxyl 40 hydrogenated castor oil, peppermint oil, povidone, propylene glycol, saccharin sodium, sodium chloride, and sodium citrate.

What dosage forms Kaletra comes in

KALETRA is available as film-coated tablets containing the following combinations of lopinavir and ritonavir: 100 mg/25 mg; 200 mg/50 mg.

KALETRA is also available as an oral solution. Each mL of KALETRA contains 80 mg of lopinavir and 20 mg of ritonavir.


Warnings and Precautions

Serious Warnings and Precautions

Tell your doctor if you or your child develop symptoms such as nausea, vomiting and abdominal pain. These may be signs of problems with your pancreas (pancreatitis). Your doctor must decide if these are related to pancreatitis and what to do about them.

BEFORE using KALETRA talk to your doctor or pharmacist if:

  • you/your child have liver problems or are infected with Hepatitis B or Hepatitis C.

  • you/your child have diabetes, or symptoms such as frequent urination, and/or increase in thirst.

  • you/your child have hemophilia: Patients taking KALETRA may have increased bleeding.

  • you/your child are taking or planning to take other medicines, including prescription, herbal and other medicines you can buy without a prescription.

  • you have heart disease or heart condition.

  • you are pregnant or breast-feeding: Pregnant or breast-feeding mothers should not take KALETRA unless specifically directed by the doctor. Be sure to tell your doctor immediately if you are or may be pregnant or if you are breast-feeding a baby. It is recommended that HIV-infected women should not breast-feed their infants because of the possibility your baby can be infected with HIV through your breast milk.

KALETRA does not reduce the risk of passing HIV to others with sexual contact or blood contamination. You should use appropriate precautions, such as practicing safe sex, and not reusing or sharing needles.

Changes in body fat have been seen in some patients taking antiretroviral therapy (see Side Effects and What to Do About Them:).


Interactions with Kaletra

KALETRA may interact with certain other medications with possible clinical effects. The use of the following medicines together with KALETRA should only take place on the basis of medical advice:

  • medicines used to treat erectile dysfunction: [e.g. Viagra (sildenafil), or Cialis (tadalafil)]. Levitra (vardenafil) should not be taken with KALETRA;

  • medicines used to lower blood cholesterol [(e.g. Crestor (rosuvastatin), Lipitor (atorvastatin), Mevacor (lovastatin) or Zocor (simvastatin)];

  • some medicines affecting the immune system [e.g. cyclosporin, Rapamycin (sirolimus), tacrolimus];

  • some medicines used to treat seasonal allergies and ear and eye infections [e.g. Decadrone (dexamethasone), Flonase (fluticasone propionate)];

  • contraceptives used to prevent pregnancy (e.g. ethinyl estradiol);

  • medicines used to treat AIDS and related infections [e.g. Agenerase (amprenavir), Lexiva (fosamprenavir), Crixivan (indinavir), Viracept (nelfinavir), Invirase (saquinavir), Videx (didanosine), Viread (tenofovir), Mycobutin (rifabutin)];

  • medicines used to treat depression [e.g. Serzone (trazodone), Wellbutrine SR (bupropion)];

  • certain heart medicines such as calcium channel antagonists [e.g. Plendil (felodipine), Adalat (nifedipine), Cardene (nicardipine)];

  • medicines used to correct heart rhythm [e.g. Cordarone (amiodarone), Tambocor (flecainide), Vascor (bepridil{†Product not available in Canada.}), systemic lidocaine, Rythmol (propafenone), quinidine, digoxin];

  • antifungals [e.g. Nizoal (ketoconazole), Sporanox (itraconazole), Vfend (voriconazole)];

  • morphine-like medicines (e.g. methadone);

  • anticonvulsants [(e.g. Tegretol (carbamazepine), Dilantin (phenytoin), phenobarbital];

  • KALETRA should not be taken once daily with Sustiva (efavirenz), Viramune (nevirapine), Agenerase (amprenavir) or Viracept (nelfinavir);

  • warfarin, certain antibiotics [e.g. Mycobutin (rifabutin), Biaxin (clarithromycin)];

  • medicines used to treat cancer (vincristine, vinblastine).

Patients taking KALETRA should not take products containing St. John’s Wort (Hypericum perforatum) as this may stop KALETRA from working properly.

KALETRA can be taken with acid reducing agents (such as omeprazole and ranitidine) with no dose adjustment.


Proper Use of Kaletra

It is important that you/your child take KALETRA every day exactly as your doctor prescribed it. Even if you feel better, do not stop taking KALETRA without talking to your doctor. Using KALETRA as recommended should give you the best chance to delay the development of resistance to the product.

It is therefore important that you remain under the supervision of your doctor while taking KALETRA.

Usual dose

The usual dose for adults is two 200/50 mg tablets (400/100 mg) or 5.0 mL of the oral solution twice a day (morning and night), in combination with other anti-HIV medicines. The doctor may prescribe KALETRA as four 200/50 mg tablets (800/200 mg) or 10.0 mL once daily in combination with other anti-HIV medicines for some patients who have not taken anti-HIV medications in the past.

The dose for children from 6 months to 12 years of age will be determined by your doctor based on the child’s height and weight.

Take KALETRA oral solution with food to help it work better.

KALETRA tablets (all strengths) can be taken with or without food. KALETRA tablets should be swallowed whole and not chewed, broken, or crushed.

Overdose

If you/your child realize you have taken more KALETRA than you were supposed to, contact your doctor or local poison control centre right away. If you cannot reach your/your child’s doctor, go to the hospital. Also, KALETRA Oral Solution contains 42% alcohol and accidental ingestion could be toxic and potentially lethal to a young child.

Missed dose

If you/your child miss a dose of KALETRA, it should be taken as soon as possible, and the next scheduled dose taken at its regular time. If it is almost time for your/your child’s next dose, do not take the missed dose. Wait and take the next dose at the regular time. Do not double the next dose.


Side Effects for Kaletra and What to Do About Them

The most commonly reported side effects of KALETRA are abdominal pain, diarrhea, feeling weak or tired, headache, nausea, vomiting and rash.

  • If you have liver disease such as Hepatitis B and Hepatitis C, taking KALETRA may worsen your liver disease.

  • Some patients have large increases in triglycerides and cholesterol (forms of fat that are found in your blood).

  • Diabetes and high blood sugar (hyperglycemia) may occur in patients taking protease inhibitors such as KALETRA. Symptoms of diabetes or high blood sugar may include frequent urination or increased thirst. Let your doctor know if you have or develop these symptoms while taking KALETRA.

  • Some patients with hemophilia have increased bleeding with protease inhibitors.

  • Changes in body fat have been seen in some patients taking antiretroviral therapy. These changes may include increased amount of fat in the upper back and neck (“buffalo hump”), breasts, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long-term health effects of these conditions are not known at this time.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Diarrhea    
Rash    
Headache    
Nausea    
Vomiting    
Tingling feeling in hands, feet and around lips    
Uncommon Chest Pain    
Pancreatitis:    
–Abdominal Pain    
–Nausea    
–Vomiting    

This is not a complete list of side effects. If you have any unexpected effects while taking this drug, contact your doctor or pharmacist.


Technical Information