Mirapex Medication Information:

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Mirapex medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Mirapex 0.180 mg
Mirapex 0.250 mg
Mirapex 0.500 mg
Mirapex 0.700 mg
Mirapex 1 mg
Mirapex 1.500 mg

Mirapex Information

Mirapex is a dopamine agonist and is used in the treatment of Parkinson's disease and is manufactured by two corporations, Boehringer-Ingelheim and Pfizer.

How it Works

It is believed that patients who suffer from the disease do so because there is a restricted supply of dopamine, which is transmitted to the brain, and Mirapex is given as treatment because it has the ability to stimulate the flow of dopamine through the brain. Another common medical problem in which Mirapex is used is Restless Leg Syndrome, or (RLS). In the case of RLS the drug is used in much the same way as it is for Parkinson's. To regulate the level of dopamine to the brain, so the muscles become relaxed and less aggravated. Mirapex comes in the form of a pill and is taken orally depending on the number of times prescribed. Patients of Parkinson's disease need to take this pill three times a day, while the Suffers of Restless Legs need only take it once a day, generally 2 to 3 hours before bedtime, although it can be taken during the day. The dosage of Mirapex depends upon the individual user's condition and intake ability, which is also considered by what other medical issues the patient, might have.

How is Mirapex Taken

If the patient has Parkinson's then the prescribed amount of drug to be taken is "one pill by mouth 3 times a day".However, if the patient taking Mirapex has RLS then it is recommended to be taken once a day by mouth about 2 to 3 hours before bedtime. The drug may be taken with or without food. Should the user happen to miss a day of the recommended dose they are advised not to double the dose the next time it is taken. This is why it is important for the patient to keep track of when they have taken the medicine on a daily schedule. Mirapex is linked to that part of the brain, which stimulates pleasure, and adventure and reward seeking, so it does carry with it some pretty common, but serious side effects. Other reasons for taking the drug Mirapex are; patients who suffer from Fibromyalgia, Depression, and other related sleeping disorders.

Side Effects

Some of the most common side effects of Mirapex include: feelings of drowsiness during daily activities such as driving, feeling faint or having dizzy spells throughout the day when sitting upright or standing up. Sometimes, nausea or a headache can occur while taking this medicine. Since the drug is in fact, a stimulant it can also produce hallucinations of the visual, audio, or taste sort. Mirapex has been known to cause compulsory control disorders as well such as intense gambling, sexual, and eating disorders in some more severe cases. While taking this drug it is also wise that one not take in any alcohol as it may cause sleepiness. It is the same if the patient is taking any other medications along with the Mirapex.

Other Names

The generic name for Mirapex is: Pramipexole, (Pram-i-pex-ole) Dihydrochloride

Safety Information:

The proper safety precautions before taking Mirapex are as follows: It is advised that you speak with your Physician before starting Mirapex if you are taking other medications that might interfere with Mirapex, if you drink alcohol, if there is a chance you might be pregnant or are pregnant or breastfeeding. Talk to your doctor if you suffer from another sleeping disorder. If have any kind of kidney disease. You should also consult your physician if after taking Mirapex you begin to experience any of the following: trouble controlling your muscles, experience low blood pressure, or have feelings of dizziness, or feel faint. Also, if you experience an allergic reaction to any of the ingredients in Mirapex then you should contact your doctor immediately. When taking Mirapex be sure to keep the drug in a tightly sealed container, out of the reach of children. Also, be sure and store the drug at room temperature and out of the direct sunlight.


The dosage use of Mirapex will vary based upon these points of interest: How well the patient responds to the drug, how well the kidneys function, what other medications the patient is currently taking, and what other medical conditions the patient may have. For patients that have RLS the starting dose is 0.125 mg daily.

0.25 mg after a four to seven day usage. If the symptoms and signs of the RLS do not. 0.75 mg daily if the condition worsens.

However, the doctor does need to wait a total of 14 days before upping the patient dosage if they suffer from any kidney problems. For patients with Parkinson's disease the prescription dosage will differ. The dosing method used in treating Parkinson's is counted in weeks on a larger scale. The starting dosage for Parkinson's is also 0.125 mg, but is to be taken 3 times a day.

By the second week the dosage would be increased to 0.25 mg 3 times a day.
On the third week it would go to 0.5 mg three times a day.

Then, on to 0.85 mg on the 4 week. Eventually, a dosage for Parkinson's disease would be set at 1.5 mg at 3 times a day. However, your Physician may need to decrease the dosage in the case of Levodopa, (Sinemet, Parcopa, Stalevo).

Visual Description:

The difference in dosage will determine the look of the pill that is taken. For instance:

  • A 0.125 mg pill is white, round and imprinted with "BI" and "83"
  • A 0.25 mg pill is oval and white and imprinted with "BIBI" and "84,84"
  • A 0.05 mg pill is white, oval and marked with "BIBI" and "85,85"
  • A 0.75 mg pill is white, round and scored and marked with "BIBI" and "90,90"
  • A 1.5 mg pill is scored, white, round and marked with "BIBI" and "91,91"

About Mirapex

What Mirapex is used for

MIRAPEX is used to treat early and late stage Parkinson’s disease. MIRAPEX provides relief of signs and symptoms of Parkinson’s disease. Signs and symptoms of the disease include: shaking (tremor), slowness in performing activities of daily living (bradykinesia), muscle stiffness (rigidity) and mood changes (depression). In late stage Parkinson’s disease, MIRAPEX will be used in combination with levodopa.

MIRAPEX is used to treat the symptoms of moderate to severe Restless Legs Syndrome (RLS) which occurs for unknown reasons. Signs and symptoms of RLS include: an urge to move the legs, usually accompanied or caused by uncomfortable and unpleasant leg sensations; symptoms begin or worsen during periods of rest or inactivity; symptoms are partially or totally relieved by movement (walking or stretching) at least as long as the activity continues; symptoms are worse or occur only in the evening or night. You may also experience difficulty falling asleep or occasional jerky legs and/or arms during sleep.

What Mirapex does

MIRAPEX belongs to a group of medicines known as “dopamine agonists”. MIRAPEX improves some of the chemical imbalance in the part of the brain affected by Parkinson’s disease or possibly, Restless Legs Syndrome.

When Mirapex should not be used

If you are allergic to MIRAPEX, or any of the nonmedicinal ingredients of the product (see What the nonmedicinal ingredients are: below). MIRAPEX is not recommended for children under 18 years of age.

What the medicinal ingredient is

MIRAPEX (pramipexole dihydrochloride monohydrate).

What the nonmedicinal ingredients for Mirapex are

Colloidal silicon dioxide, cornstarch, magnesium stearate, mannitol and povidone.

What dosage forms Mirapex comes in

MIRAPEX (pramipexole dihydrochloride monohydrate) is supplied in bottles of 90 tablets for the 0.25 mg, 0.5 mg, 1.0 mg, and 1.5 mg tablets; the 0.125 mg tablets are available in blister pack of 30 tablets.

Warnings and Precautions

You are warned of a sudden onset of sleep condition which may occur without warning, while taking MIRAPEX. You should not operate machinery or engage in activities that require alertness, as you may put yourself and others at risk of serious injury or death. This sudden onset of sleep condition has also been reported in patients taking other anti-Parkinson drugs of the same class.

Studies of people with Parkinson’s disease show that they may be at an increased risk of developing melanoma (a form of skin cancer) when compared to people without Parkinson’s disease. It is not known if this problem is associated with Parkinson’s disease or the drugs used to treat Parkinson’s disease. MIRAPEX is one of the drugs used to treat Parkinson’s disease; therefore, patients treated with MIRAPEX should have periodic skin examinations.

Patients and caregivers should be aware of the fact that abnormal behavior such as pathological gambling, increased sexual desire, excessive sexual activity, compulsive shopping or binge eating have been reported. Those changes have also been reported in patients taking other anti-Parkinson drugs of the same class.

BEFORE you use MIRAPEX talk to your doctor or pharmacist:

  • if you have any health problems, especially kidney problems or blood pressure problems;

  • if you have any unusual conditions related to your eyes or eyesight;

  • if you have previously taken MIRAPEX and became unwell;

  • if you have any allergies or reactions to foods or drugs;

  • if you are pregnant or intend to become pregnant;

  • if you are breast feeding;

  • if you are taking any other medications, including any drugs you can buy without a prescription.

  • if you drive a vehicle or perform hazardous tasks during your work.

Interactions with Mirapex

Other medications may be affected by MIRAPEX or may affect how MIRAPEX works. Do not take any other medication, including over-the-counter medications or herbal products unless your doctor tells you to. Tell any other doctor, dentist or pharmacist that you talk to that you are taking MIRAPEX.

Avoid alcohol or other sedatives while taking MIRAPEX.

Proper Use of Mirapex

Usual Adult dose

Parkinson’s Disease

Take MIRAPEX in equal doses, three times daily as prescribed by your doctor. Dosages should be increased gradually from a starting dose of 0.125 mg three times daily and should not be increased more frequently than every 5 to 7 days. It is important that your doctor increases your dosage of MIRAPEX gradually to avoid side effects and to achieve the best therapeutic effect. Your dose will probably change each week until your doctor and you decide what the best dose is for you. Make sure that you only use the tablet strength that your doctor has prescribed. The maximal recommended dose of MIRAPEX is 4.5 mg per day. Lower doses are recommended for patients with kidney disease.

Your doctor may decide to lower your dose of levodopa to prevent excessive side effects and to make sure that you are getting the best results from both drugs. Pay close attention to your doctor’s instructions and never change the dose of either drug yourself.

You should not change the dose or discontinue treatment with MIRAPEX without the recommendation of your doctor.

You may take MIRAPEX without food or with food if you find that you feel sick to your stomach while taking the tablets.

Restless Legs Syndrome

The recommended starting dose of MIRAPEX is 0.125 mg taken once daily (2-3 hours before bedtime) as prescribed by your doctor. If it is required, your doctor may change the dose every 4-7 days to achieve the best therapeutic effect. Tablets should be swallowed with water, and can be taken either with or without food. The maximal recommended dose of MIRAPEX is 0.50 mg per day.

Do not stop taking MIRAPEX suddenly, as this may result in worsened RLS symptoms. Talk to your doctor about slowly stopping the medication if necessary.


If you accidentally take too many tablets, you should get medical help immediately; either by calling your doctor or by going to the nearest hospital (do not drive yourself). Always take the labelled medicine container with you whether or not there are any MIRAPEX tablets left.

Missed dose

If you forget to take a dose, take it as soon as you remember, then carry on as before. However, if it is almost time for your next dose, skip the dose you missed and take the next dose when you are supposed to. Do not take more than one dose at a time.

MIRAPEX has been prescribed for you. Do not give these tablets to anyone else, even if you think they have the same condition as you.

Side Effects for Mirapex and What to Do About Them

You should be aware that prescription medicines carry some risks and that all possible risks may not be known at this stage. Discuss with your doctor the risks of taking MIRAPEX against the expected benefits.

  • MIRAPEX may cause unwanted effects such as nausea, constipation, sleepiness, dream abnormalities, amnesia, fatigue, muscle weakness, restlessness, weight decrease, visual disturbance, accidental injury and confusion. If you do experience any unusual or unwanted effects while you are taking MIRAPEX, be sure to tell your doctor. It is important that he/she knows of any unwanted effects to determine the best dose of MIRAPEX for you.

  • MIRAPEX does not usually affect people’s normal activities. However, some people may feel dizzy or sleepy while taking MIRAPEX, especially during the first few weeks of treatment.

  • If you are taking MIRAPEX for RLS you may notice an increase in your symptoms in the early morning or the afternoon/early evening hours. If this happens, please, let your doctor know.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Dyskinesia (Difficulty performing voluntary movements)    
Hallucinations (see, hear, smell, taste or feel something that is not there)    
Insomnia (Difficulty falling asleep)    
Low blood pressure with dizziness when rising to a sitting or standing position. You may feel sick, light-headed, faint or you may sweat.    
Uncommon Behavioral changes such as compulsive gambling, compulsive shopping, changes in sexual desire or sexual activity, increased eating    
Delusion (a false belief, despite incontrovertible evidence, that something is false)    
Paranoia (unrealistic and excessive anxiety and worry)    
Sudden onset of sleep    

Do not be alarmed by this list of possible side effects. You may not experience any of them. This is not a complete list of side effects. For any unexpected effects while taking MIRAPEX, contact your doctor or pharmacist immediately, so that these effects may be properly addressed.


Technical Information