Lioresal Medication Information:

Price Break On Lioresal
Generic is available for less money: Generic Baclofen

Lioresal medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Lioresal 10 mg
Lioresal DS 20 mg

What is Lioresal Intrathecal?

Lioresal Intrathecal contains an active substance called baclofen. It is available as a solution which is contained in an ampul (glass vial).

The solution is injected or infused into the fluid space around the spinal cord by use of a special pump which is implanted under the skin. From the pump a constant amount of the solution is delivered into the fluid space around the spinal cord through a tiny tube.

Due to the beneficial effect on muscle contractions and the consequent relief from pain, Lioresal Intrathecal improves your mobility and your ability to manage your daily activities without aid, Lioresal also helps you to benefit more from physiotherapy.

Before Treatment with Lioresal Intrathecal

Lioresal Intrathecal is suitable for many patients with muscle spasms, but not for all. Therefore, tell your doctor if you:

  • have had any unusual sensitivity (rash or other possible signs of allergy) to previous baclofen (e.g., Lioresal tablets) use

  • have any kind of infection

  • have certain mental illnesses accompanied by confusion

  • have epilepsy (seizures)

  • ever had heart problems

  • ever had kidney problems

  • have breathing problems

  • have acute pain in your stomach or intestine

  • have disturbed blood circulation in your brain

  • have ever experienced sudden episodes of high blood pressure, anxiety, excessive sweating, “goose flesh”, pounding headache, and unusually slow heartbeat due to an overreaction of your nervous system to stimuli such as distension of the bladder and intestine, skin irritation and pain

Some medicines may interfere with the action of Lioresal Intrathecal. Tell your doctor what other prescription and nonprescription (over-the-counter) medicines, if any, you are taking. Your doctor may change the dosage or sometimes stop one of the medicines. This is particularly important for the following medicines:

  • medicines used to treat high blood pressure

  • medicines used to help you sleep or calm you down

  • medicines which act on the central nervous system

Be careful if you drink alcoholic beverages during treatment with Lioresal Intrathecal as you may feel more sleepy or dizzy than usual.

Lioresal Intrathecal may make you feel sleepy or dizzy. So be careful when driving a car or using a machine or doing other things that need your careful attention until you are feeling normal again.

Women should tell their doctor if they are pregnant, plan to become pregnant or are breast-feeding. The doctor will decide if you may receive Lioresal Intrathecal in these special situations. Only very small quantities of Lioresal pass into the breast milk. Ask your doctor if you want to breast-feed.


Signs of overdose may appear suddenly or insidiously e.g., by a malfunctioning of the pump. It is very important that you and those caring for you recognize signs of overdosage. If you experience any one or a combination of the following symptoms, tell your doctor without delay as the amount of drug you receive may be too high:

  • unusual muscular weakness (too little muscle tone)

  • sleepiness

  • lightheadedness or dizziness

  • excessive salivation

  • nausea or vomiting

  • difficulties in breathing, seizures or loss of consciousness

  • abnormal low body temperature

What Side Effects for Lioresal Can Lioresal Intrathecal Have?

Like all medicines, Lioresal Intrathecal, along with its desired effects, may also cause some side effects. These occur more often at the start of treatment during your hospital stay but they may also occur later and should be checked with your doctor.

More common: drowsiness, weakness in the legs, too little or too much muscle tone, dizziness, headache, sleepiness, feeling sick and/or vomiting, tingling in hands and feet, slurred speech, blurred vision.

Less common: unusually slow heartbeat, constipation.

Rare: swelling of the ankles, feet, or lower legs, loss of muscle coordination, insomnia, memory loss, confusion, feeling of anxiety, feeling of depression, mood or mental changes, hallucinations, difficulty in swallowing, decreased appetite, dry mouth, itching, continuous uncontrollable eye movements, diarrhea, urinary incontinence, abnormally low body temperature.

Tell your doctor if you notice any other effect.


Technical Information