Asacol Medication Information:

Price Break On Asacol
Generic is available for less money: Generic Novo-5 ASA EC (Mesalamine)

Asacol medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Asacol 400 mg
Asacol 800 mg

Asacol General Information

Asacol is mainly used for ulcerative colitis, a particular type of bowel disease. This medication does not cure this condition, but it does decrease symptoms like diarrhea, stomach pain and rectal bleeding caused by the swelling and irritation in the rectum or colon. This is an aminosalicylate anti-inflammatory drug, therefore thought to work by stopping the body from producing natural chemicals that may be causing swelling and pain. This medicine is also taken to treat Crohn's disease. It is only available by prescription and comes in a plain tablet, eneric-coated tablet, extended-release capsule and delayed-response tablet.

How Asacol Works

Because Asacol is part of the group aminosalicylates, it is works by restraining the production of inflammatory chemicals in the colon's lining. Because of this, the medication lowers the production of leukotrienes and prostaglandins, both that are found to lead to inflammation of ulcerative colitis. The patented delivery system of Asacol gets the medicine where it is mostly needed in the body. After swallowed, the special coating of Asacol allows it to travel throughout the stomach until it gets to the beginning of the colon. Once here, the tablet will release its active ingredient, mesalamine, that will work its way through the colon. This ingredient helps to decrease inflammation within the lining of the rectum and colon.

How to take Asacol

The dose of Asacol that is prescribed by a physician will depend on severity of the condition, other current medical conditions, and other medications currently taking. This medication comes in a tablet form and typically taken orally 3 times each day. The medicine can be taken with or without food and should be taken with food if it upsets your stomach.

The Asacol tablet is delayed-release with a special coating. To protect this coating, it should not be cut, chewed or crushed. It should be taken at the very same time every day to control even levels in the blood. The dose recommended for mild to moderate active ulcerative colitis is two 400 mg tablets 3 times each day for a total of six weeks. One the ulcerative colitis goes into remission, the dosage may be decreased to 1600 mg each day that is divided into separate doses. This medication must be stored at room temperature and away from any heat and moisture.

Side Effects

The following are serious side effects and Asaco should be stopped immediately and emergency help needs to be called right away: allergic reactions such as swelling of the lips, face, throat or tongue, difficulty breathing and hives. Other serious side effects include cramping, headache, severe stomach pain and bloody diarrhea. A doctor should be called with any of these. Less serious side effects include: vomiting, diarrhea, gas, sore throat, fever, constipation, dizziness, fatigue and skin rash.

Other brand names for Asacol include:

  • Lialda
  • Pentasa

Safety Information:

Your doctor needs to know if you are allergic to any particular drug or have stenosis (stomach condition), History of Azulfidine (allergy to sulfasalazine), kidney or liver disease or a heart condition.


The average dose to begin taking Asacol is 2400 mg daily for someone with active ulcerative colitis.

Visual Description

The tablets come in a red color, about one inch long and oval shaped. The capsules comes in a blue color, one inch in length and oval shaped

Asacol Facts

The drug Asacol is a registered trademark of Medeva Pharma Suisse AG, licensed by Procter & Gamble Pharmaceuticals, Inc.

Clinical trials of Asacol evaluated the use of the drug in 3,685 patients with inflammatory bowel disease.

In clinical trials of Asacol, adverse effects in patients given the drug were quite similar to those of patients given a placebo.

Asacol obtained original or tentative approval from the FDA on January 31, 1992.


Technical Information