Vfend 200 mg

Generic Name: Voriconazole 200 mg
Vfend 200 mg Image

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Best Value On Brand Vfend 200 mg
Price: $68.05 per tab!
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Vfend 200 mg Prescription Required
10 tabs for $680.50 ($68.05 per tab)
Vfend from online pharmacy: India
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Best Value On Generic Voriconazole 200 mg
Price: $15.60 per tab!
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Voriconazole 200 mg Prescription Required
30 tabs for $468.13 ($15.60 per tab)
Voriconazole from online pharmacy: Canada
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Vfend 200 mg is available from our online pharmacy for less money than you'd spend locally. If you like the convenience of ordering from your home, you can order your prescription online, or speak with one of our customer service representatives on the phone. Call us, The Drug Company, toll free at 1-888-254-3038. Prior to taking Vfend 200 mg, please consult with your doctor or health professional to see if this medication is right for you. Many customers have saved even more money by speaking with their doctor about a generic substitute.

About Vfend

What Vfend is used for

VFEND is prescribed by your doctor to treat certain fungal infections, specifically Aspergillus or Candida infections.

What Vfend does

VFEND works by killing or interfering with the growth of fungi which helps stop the infection.

When Vfend should not be used

  • If you are allergic to voriconazole or any of the other ingredients of VFEND (see What the important nonmedicinal ingredients are:).

  • If you are taking other medication that must not be taken with VFEND (see Interactions with This Medication:).

What the medicinal ingredient is and what dosage forms does Vfend come in

  • Voriconazole tablets, 50 mg and 200 mg

  • Voriconazole powder for oral suspension, 40 mg per mL

  • Voriconazole for injection, 200 mg per vial

What the important nonmedicinal ingredients for Vfend are

  • voriconazole tablets:

    croscarmellose sodium, hypromellose, lactose monohydrate, magnesium stearate, povidone, pregelatinized starch, titanium dioxide and triacetin

  • voriconazole powder for oral suspension:

    anhydrous citric acid, colloidal silicon dioxide, natural orange flavor, sodium benzoate, sodium citrate dihydrate, sucrose, titanium dioxide, and xanthan gum

  • voriconazole for injection:

    sulphobutylether-β-cyclodextrin sodium (SBECD)

VFEND has been prescribed for you. Do not allow anyone else to take it. This product should only be taken under the supervision of a doctor.


Warnings and Precautions

  • Some medications should not be taken during VFEND treatment (see listing under “Interactions with This Medication:”)

  • VFEND may cause irregular heartbeat and rarely cardiac arrest and death

  • VFEND may cause disturbances in vision

  • VFEND may cause liver problems

  • VFEND may cause severe skin reactions VFEND may cause harm to the fetus in pregnant woman

For more information, see Warnings below and “Side Effects and What to Do About Them:”.

Take special care with VFEND

Before being treated with VFEND, tell your doctor if:

  • you have any of the following conditions: history of heart disease, or an irregular heart beat.

  • you have had any drug allergies including allergic reactions to other azoles.

  • you are suffering from, or have ever suffered from liver disease.

  • You are suffering from, or have ever suffered from kidney disease.

  • You are already being treated with certain medication (see Interactions with This Medication: )

  • you think you have galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption, please check with your doctor before starting to take VFEND tablets since they contain lactose monohydrate.

  • you think you have sucrose intolerance, fructose intolerance, sucrase-isomaltase deficiency or glucose-galactose malabsorption, please check with your doctor before starting to take VFEND powder for oral suspension since it contains sucrose.

  • you are pregnant: VFEND must not be taken during pregnancy, unless indicated by your doctor. Effective contraception must be used in women of child-bearing potential. Contact your doctor immediately if you become pregnant while taking VFEND.

  • you are breast-feeding: VFEND must not be taken during breast-feeding. Ask your doctor or pharmacist for advise before taking any medicine while breast-feeding.

While being treated with VFEND:

  • tell your doctor immediately if you develop a severe skin rash or blisters.

  • strong sunlight should be avoided while being treated with VFEND. Tell your doctor if you develop an increased sensitivity of skin to the sun.

  • your doctor may wish to monitor the function of your liver and kidney by doing blood tests.


Interactions with Vfend

Taking other medicines with VFEND

It is very important that you inform your doctor or pharmacist if you are taking or have taken any other medicines, even those that are obtained without a prescription. Some medicines affect the way VFEND works and dosage adjustments or monitoring may be necessary, such as for the following:

  • Cyclosporine (a medicine used in transplant patients)

  • Tacrolimus (a medicine used in transplant patients)

  • Tricyclic antidepressants

  • Antiarrhythmics (drugs that stabilize heart function such as procainamide, amiodarone, quinidine, sotalol)

  • Antipsychotic drugs

  • HIV protease inhibitors

  • Macrolide antibiotics

  • Methadone

  • Oral contraceptives

  • Short-acting opiates (e.g. alfentanil, sufentanil)

  • Some oral anticoagulants (e.g. warfarin, coumarin)

The following list of medicines must not be taken during your course of VFEND treatment:

  • Terfenadine{*Not marketed in Canada.} (a medicine for allergy)

  • Astemizole* (a medicine for allergy)

  • Cisapride* (a medicine for stomach problems)

  • Pimozide (a medicine for treating mental illness)

  • Quinidine (a medicine for irregular heart beat)

  • Rifampicin (a medicine for treating tuberculosis)

  • Carbamazepine (a medicine used to treat seizures)

  • Long-acting barbiturates (medicines for severe insomnia and seizures) such as phenobarbital

  • Sirolimus (used in transplant patients)

  • Rifabutin (a medicine for fungal infections)

  • Ergot Alkaloids: ergotamine and dihydroergotamine (a medicine for migraines)

  • Ritonavir (high dose) and efavirenz (standard dose) (medicines for the treatment of HIV)

  • St John’s Wort


Proper Use of Vfend

Usual Adult dose

Your doctor will determine your dose depending on your weight and the type of infection (or suspected infection) you have.

Always take VFEND exactly as directed by your doctor. You should check with your doctor or pharmacist if you are unsure. Never change the dose yourself.

VFEND Injection

During the first 24 hours, you will be administered 2 doses of 6 mg/kg (12 hours apart).

After the first 24 hours:

  • If you have an Aspergillus infection, you will be administered 4 mg/kg, twice a day.

  • If you have a Candida infection, you will be administered 3 mg/kg or 4 mg/kg, twice a day.

VFEND Tablets

Infection First 24 hours (2 doses 12 hours apart) After the first 24 hours
≥40 kg <40 kg ≥40 kg <40 kg
Aspergillus 400 mg 200 mg 200 mg twice a day 100 mg twice a day
Candida 400 mg

It has been shown that taking all doses at the appropriate times may greatly increase the effectiveness of your medicine.

VFEND tablets must be taken at least one hour before or two hours after a meal. Swallow the tablet whole with some water.

VFEND oral suspension must be taken one hour before or following a meal. Shake the closed bottle for approximately 10 seconds before each use. The suspension should only be administered using the oral dispenser supplied with each pack.

VFEND oral suspension should not be mixed with any other medication or flavoring agent, and should not be further diluted with water or any other drinks.

If you have liver disease, your doctor may prescribe a lower dose of VFEND.

Continue taking VFEND until your doctor tells you to stop. Do not stop treatment early because your infection may not be cured. Patients with a weakened immune system or those with difficult infections may require long term treatment to prevent the infection from returning.

Overdose

If you take more tablets or more suspension than prescribed (or if someone else takes your tablets or your suspension) you must seek medical advice, contact your regional poison control centre, or go to the nearest hospital emergency department immediately. Take your box of VFEND tablets or bottle of VFEND Oral Suspension with you.

Missed dose

If you miss taking a dose of VFEND, just take the next dose when it is due. Do not take a double dose to make up for the forgotten dose.


Side Effects for Vfend and What to Do About Them

Like all medicines, VFEND can have side effects. If any side effects occur, most are likely to be minor and temporary. However, some may be serious and need medical attention.

The most commonly reported side effects are visual disturbances (blurring of vision, reduced vision, colour vision change and increased sensitivity to light), fever, rash, nausea, vomiting, diarrhea, headache, swelling of the extremities and stomach pains.

Other reported side effects include: changes in heart rate or rhythm, changes in blood pressure, blood cell changes, blood chemistry changes, dizziness, itchiness, weakness, back pain, chest pain, flu like symptoms, facial swelling, hallucinations and other nervous symptoms, tingling, cough, breathing difficulty, hair loss, pain and irritation of the eyes, joint pain.

Check with your doctor immediately if chills, fever, flushing, sweating, muscle aches or pains, or other fIu-like symptoms occur, especially if they occur shortly before, or together with a skin rash. Also, contact your doctor in case of a fast heartbeat, chest tightness or faintness. Very rarely, these effects may be the first signs of a serious reaction to this medication.

Contact your doctor if you suffer persistent abdominal pain and tenderness or vomiting as this may be a sign of a serious condition (pancreatitis).

Driving and using machines

VFEND may cause changes to vision, including blurring and/or photophobia (sensitivity to light). The majority of visual symptoms appeared to spontaneously resolve within 60 minutes. While being treated with VFEND you must avoid potentially hazardous tasks, such as driving or operating machinery if you perceive any change in vision. You should not drive at night while taking VFEND.

If any of these side effects persist or are troublesome, please tell your doctor.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Uncommon Cardiac arrest  
Irregular heartbeat  
Visual disturbances    
Severe skin reactions    
Liver problems (yellowing of the eyes or skin, itching, feeling more tired than usual or like you have the flu, stomach pains or nausea and vomiting)  

This is not a complete list of side effects. If you notice any unexpected side effects while using VFEND, please contact your doctor or pharmacist.


Technical Information