Remeron RD

Remeron RD Medication Information:

Price Break On Remeron RD
Generic is available for less money: Generic Mirtazapine

Remeron RD medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Remeron RD 15 mg
Remeron 30 mg
Remeron RD 45 mg

About Remeron RD

What Remeron RD is used for

REMERON RD belongs to a group of medicines known as antidepressants.

REMERON RD has been prescribed to you to relieve your symptoms of depression. Treatment with these types of medications is most safe and effective when you and your doctor have good communication about how you are feeling.

What Remeron RD does

The way REMERON RD works to treat depression is unknown. REMERON RD is thought to have an effect in the brain on chemicals called serotonin and norepinephrine.

When Remeron RD should not be used

Do not use REMERON RD if you are allergic to it or any of the components (see What the important nonmedicinal ingredients are:).

What the medicinal ingredient is


What the important nonmedicinal ingredients for Remeron RD are

Aspartame (contains phenylalanine), citric acid, crospovidone, hydroxypropyl methylcellulose, magnesium stearate, mannitol, microcrystalline cellulose, natural and artificial orange flavour, polymethyl acrylate, povidone, sodium bicarbonate, starch, sucrose.

What dosage forms Remeron RD comes in

Orally disintegrating tablet as a white, flat-faced, round, bevelled edge tablet with a characteristic orange odour, coded with TZ1, TZ2, and TZ4 for the 15 mg, 30 mg, and 45 mg tablets, respectively.

Warnings and Precautions

During treatment with these types of medications, it is important that you and your doctor have good ongoing communication about how you are feeling.

BEFORE you use REMERON RD, talk to your doctor or pharmacist

  • about all your medical conditions, including a history of seizures, liver or kidney disease, heart problems, diabetes, low blood pressure, glaucoma (increased intra-ocular pressure), high cholesterol and/or high triglycerides (fats in the blood), difficulties in urinating as a result of an enlarged prostate, psychiatric diseases such as schizophrenia and bipolar disorder (alternating periods of elation/overactivity and depressed mood)

  • about any medications (prescription or nonprescription) which you are taking (refer to the next section for specific Interactions with This Medication:)

  • about any natural or herbal products you are taking (e.g., St. John’s wort)

  • if you are pregnant or thinking of becoming pregnant, or if you are breastfeeding;

  • about your habits of alcohol consumption.

  • if you have been told by your doctor that you have an intolerance to some sugars

Remeron RD contains a source of phenylalanine. May be harmful for people with phenylketonuria.

REMERON RD is not for use in children under 18 years of age.

Refrain from potentially hazardous tasks, such as driving a car or operating dangerous machines, until you are certain that this medication does not affect your mental alertness or physical coordination.

Contact your physician before stopping or reducing your dosage of REMERON RD. Symptoms such as dizziness, abnormal dreams, electric shock sensations, agitation, anxiety, difficulty concentrating, headache, tremor, nausea, vomiting, sweating or other symptoms may occur after stopping or reducing the dosage of REMERON RD. Such symptoms may also occur if a dose is missed. These symptoms usually disappear without needing treatment. Tell your doctor immediately if you have these or any other symptoms. Your doctor may adjust the dosage of REMERON RD to alleviate the symptoms.

Effects on Pregnancy and Newborns

Post-marketing reports indicate that some newborns whose mothers took an SSRI (Selective Serotonin Reuptake Inhibitor) or other newer antidepressants, such as REMERON RD, during pregnancy have developed complications at birth requiring prolonged hospitalization, breathing support and tube feeding. Reported symptoms include: feeding and/or breathing difficulties, seizures, tense or overly relaxed muscles, jitteriness and constant crying. In most cases, the newer antidepressant was taken during the third trimester of pregnancy. These symptoms are consistent with either a direct adverse effect of the antidepressant on the baby, or possibly a discontinuation syndrome caused by sudden withdrawal from the drug. These symptoms normally resolve over time. However, if your baby experiences any of these symptoms, contact your doctor as soon as you can.

If you are pregnant and taking an SSRI or other newer antidepressants, such as REMERON RD, you should discuss the risks and benefits of the various treatment options with your doctor. It is very important that you do NOT stop taking these medications without first consulting your doctor.

Interactions with Remeron RD

Do not use REMERON RD if you are taking or have recently taken monoamine oxidase inhibitors (e.g., phenelzine sulphate, moclobemide, tranylcypromine sulphate, or selegeline), thioridazine, or pimozide.

You should tell your doctor if you are taking or have recently taken any medications (prescription, non-prescription or natural/herbal), especially:

  • other antidepressants, such as SSRIs and certain tricyclics

  • other drugs that affect serotonin such as tryptophan, triptans, lithium, tramadol, linezolid, St. John’s wort

  • ketoconazole(medicine for treating fungal infections)

  • cimetidine (used to treat reflux and stomach ulcers)

  • erythromycin [used to treat bacterial infections (antibiotic)]

  • drugs used to treat Human Immunodeficiency Virus (HIV), such as a combination of fosamprenavir and ritonavir

  • nefazodone (used to treat depression)

  • certain drugs used to treat epilepsy, such as carbamazepine and phenytoin

  • rifampicin (used to treat tuberculosis)

  • warfarin (used to prevent blood clotting)

  • benzodiazepines (e.g., midazolam, oxazepam and diazepam)—as REMERON RD may add to the sedative effects of these agents.

Avoid alcoholic drinks while taking REMERON RD.

Proper Use of Remeron RD

Usual dose

It is very important that you take REMERON RD exactly as your doctor has instructed. Generally, most people take between 15 mg and 45 mg per day.

How to take REMERON RD

  • Never increase or decrease the amount of REMERON RD you, or those in your care if you are a caregiver or guardian, are taking unless your doctor tells you to, and do not stop taking this medication without consulting your doctor (see Warnings and Precautions: when taking REMERON RD).

  • Some symptoms may begin to improve within about two weeks, but significant improvement can take several weeks. Continue to follow the doctor’s instructions.

  • The tablets should be taken at the same time each day, preferably as a single evening dose (prior to sleep). Do not chew them.

  • Keep taking your tablets until the doctor tells you to stop. The doctor may tell you to take your medicine for several months. Continue to follow the doctor’s instructions.

  • If you forget to take your evening dose, do not take the missed dose the next morning. Continue treatment in the evening (prior to sleep) with your normal dose.

The tablet(s) should be taken as follows:

(See package insert for illustrations.)

  • In order to prevent crushing the tablet, do not push against the tablet pocket.

  • Each strip contains six tablet pockets, which are separated by perforations. Bend the strip as indicated. Tear off one tablet pocket along the dotted lines.

  • Carefully peel off the lidding foil, starting in the corner indicated by the arrow.

  • Take out the tablet (making sure your hands are dry) and place it on the tongue . The tablet will rapidly disintegrate and can be swallowed without water.

  • The tablet should be used immediately after removal from its blister; once removed, it cannot be stored.

  • Do not attempt to split the tablet.


If you have taken a large number of tablets all at once, contact your doctor, the nearest hospital emergency department or the nearest Poison Control Centre immediately, even though you may not feel sick. Show the doctor your pack of pills.

Missed dose

Do not take a double dose to make up for forgotten doses. If you forget to take your evening dose, do not take the missed dose the next morning. Continue treatment in the evening (prior to sleep) with your normal dose.

Side Effects for Remeron RD and What to Do About Them

  • You may experience some side effects, such as increase in appetite, swollen ankles or feet, occasional dizziness or faintness (especially when you get up quickly from a lying or sitting position), nausea and headache. In rare cases, other effects may include rash, abnormal sensation in the skin (e.g., burning, stinging, tickling or tingly), increased number of white blood cells, involuntary trembling of muscles (tremor), dry mouth, tiredness. In very rare cases, other effects may include abnormal sensations in the mouth, sensations of numbness in the mouth and swelling in the mouth. Some side effects are temporary. Consult your doctor if you experience these or other side effects, as the dose may have to be adjusted.

New and Worsened Behavioural Problems

Particularly in the first few weeks of treatment, or when doses are adjusted, a small number of patients taking drugs of this type may feel worse instead of better; for example, they may experience unusual feelings of agitation, hostility or anxiety, or have impulsive or disturbing thoughts such as thoughts of self-harm or harm to others. Should this happen to you, or to those in your care if you are a caregiver or guardian, consult your doctor immediately; do not discontinue your medication on your own.

Stop taking the drug and contact your doctor immediately if you experience an allergic reaction or any severe or unusual side effects.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Drowsiness which can lead to impaired concentration, generally occurring during the first few weeks of treatment    
Weight gain    
Rare Bruising and/or unusual bleeding and symptoms of infection such as sudden high fever, sore throat, mouth ulcers, severe digestive system disturbances or other signs of infection (symptoms of blood cell disturbances)   a  
Convulsions (loss of consciousness with uncontrollable shaking)     a
Fainting/loss of consciousness    
Nightmares/vivid dreams, agitation or confusion    
Hallucinations (strange visions or sounds)    
Mania (feeling elated or emotionally ‘high’ )   a  
Feeling restless and unable to stand still    
Uncontrolled, sudden movements    
Restless legs (feeling of unrest during night mainly located in the legs combined with sudden muscle contractions in the legs)    
Pain in the joints or muscles    
Jaundice (yellowing of eyes or skin; dark urine)   a  
Symptoms of depression (anxiety and disturbed sleep)    
New or worsened emotional or behavioural problems   a  
Very Rare A combination of symptoms such as unexplainable fever, sweating, increased heart rate, diarrhoea, (uncontrollable) muscle contractions, shivering, overactive reflexes, restlessness, mood changes and unconsciousness (can be signs of serotonin syndrome)   a  
a. If you think you have these side effects, it is important that you seek medical advice from your doctor straight away.

This is not a complete list of side effects. For any unexpected effects while taking REMERON RD, contact your doctor or pharmacist.


Technical Information