Femara 2.500 mg

Generic Name: Letrozole (Generic equivalent to Femara) 2.500 mg
Femara 2.500 mg Image

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Femara Facts

FEMARA or letrozole has been tested in clinical trials since 1997.

Estrogen receptor-positive breast cancer reoccurs in about one third of women after they are declared cancer-free.

Long term benefits of FEMARA are being studied in ongoing trials.

FEMARA is used to prevent a recurrence of hormone receptor-positive breast cancer.

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Best Value On Brand Femara 2.500 mg
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Femara 2.500 mg Prescription Required
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Femara from online pharmacy: India
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Best Value On Generic Letrozole (Generic equivalent to Femara) 2.500 mg
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Letrozole (Generic equivalent to Femara) 2.500 mg Prescription Required
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Letrozole (Generic equivalent to Femara) from online pharmacy: India
Guaranteed US Delivery

Femara 2.500 mg is available from our online pharmacy for less money than you'd spend locally. If you like the convenience of ordering from your home, you can order your prescription online, or speak with one of our customer service representatives on the phone. Call us, The Drug Company, toll free at 1-888-254-3038. Prior to taking Femara 2.500 mg, please consult with your doctor or health professional to see if this medication is right for you. Many customers have saved even more money by speaking with their doctor about a generic substitute.

Femara General Information

Femara or Letrozole tablets were approved in 1997 by the Food and Drug Administration to effectively help post menopausal women that have been diagnosed with early hormone receptor positive early breast cancer. Femara has shown to be effective for women throughout different stages of early hormone receptor-positive breast cancer including early, locally advanced and mastistic stages. Femara is also known to help lower the risk of returning breast cancer diagnosis and has been shown to reduce the reoccurrence within several months of completion of five years worth of tamoxifen therapy. For those patients with an advanced breast cancer diagnosis, Femara helped to reduce the disease progression. Femara has not been proven to improve the survival rate versus that of tamoxifen.

How does Femara work, What does it do?

Hormone-dependent breast cancers have molecules made from protein known as estrogen receptors. When there is no estrogen present, these receptors remain inactive, however if these estrogen receptors are exposed to more estrogen, a possible chain reaction of cellular growth, leading to tumor development can occur. Tumors that have estrogen receptors are known as estrogen receptor-positive or ER+. They can often be treated with a type of hormone therapy. Laboratory tests determine if breast cancer is either estrogen receptive negative or ER- or if it is estrogen receptive positive. Tumors have to be diagnosed as estrogen receptor plus, estrogen receptor negative or estrogen receptor unknown in order for a doctor to prescribe Femara. As a form of hormone therapy, or an aromatase inhibitor, Femara works by lowering the amount of estrogen produced by postmenopausal women. Tamoxifen also enables estrogen from being used to help cancer gain in size. Femara's main goal is to prevent cancerous cells from further development. It does this by allowing them to "starve" or not get any estrogen, because of this they do not have a chance to grow.

When and how often is Femara taken?

Femara only has to be taken once a day, however it should be taken at approximately the same time every day, and if you miss a dose an extra dose does not need to be taken, just take your dose at the regular time the next day.

What are the side effects of Femara?

Some of the side effects of Femara are, night sweats and hot flashes, nausea, increased cholesterol as well as an increase in weight, fatigue and brittle bone fractures. Some women have also experienced dizziness as well as drowsiness while taking Femara, women prescribed femara should be cautious when driving or operating heavy machinery. Some less common reported side effects are blood clots and vaginal bleeding, endometrial cancer and heart attack as well as stroke and osteoporosis. If you experience any of these side effects for a prolonged period of time, you should advise your doctor.

Other brand names for Femara:

Femara may also be known as Letrozole.

Safety Information:

Certain individuals may not take Femara. Patients that are premenopausal should not take Femara. Pregnant women or women who could become pregnant should also not take Femara, because it could pose a harmful risk to the unborn child. Femara is intended for post menopausal women only.


Femara comes in 2.5 milligram dosages, and only needs to be taken on a once daily basis.

Visual Description:

Femara is a small yellow tablet with FV and CG inscribed on them.

About Femara

What Femara is used for

  • The adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer;

  • The extended adjuvant treatment of hormone receptor positive early breast cancer in postmenopausal women who have received approximately 5 years of prior standard adjuvant tamoxifen therapy.

  • The first-line therapy in postmenopausal women with advanced breast cancer; and

  • The hormonal treatment of advanced metastatic breast cancer in women with natural or artificially-induced postmenopausal status, who have disease progression following antiestrogen therapy.

What Femara does

Estrogen is a normally occurring female sex hormone that stimulates normal breast tissue and the growth of some types of breast cancer. FEMARA is an aromatase inhibitor which acts by binding to aromatase, a substance needed to make estrogen. As a result, the production of estrogen and the growth of breast cancer are reduced.

What is adjuvant therapy

Adjuvant therapy in breast cancer refers to treatment following breast surgery (the primary or initial treatment) in order to reduce the risk of recurrence. The purpose of adjuvant therapy with FEMARA is to treat hormone receptor-positive early breast cancer, after surgery, in postmenopausal women to reduce the risk of recurrence.

What is extended adjuvant therapy

The purpose of extended adjuvant therapy with FEMARA is to treat hormone receptor-positive early breast cancer in postmenopausal women who have received approximately 5 years of prior standard adjuvant tamoxifen therapy in order to prevent recurrence. Treating breast cancer with FEMARA beyond the standard 5 years of hormone therapy is called “extended adjuvant therapy”.

When Femara should not be used

FEMARA should not be used in children and adolescents under 18 years of age.

Do not take FEMARA if you

  • have ever had an unusual or allergic reaction to letrozole or any other ingredient in FEMARA;

  • still have menstrual periods;

  • are pregnant or breast-feeding, as FEMARA may harm your baby.

What the medicinal ingredient is


What the nonmedicinal ingredients for Femara are

FEMARA also contains the following nonmedicinal ingredients needed to make the tablets: cellulose compounds (microcrystalline cellulose and methylhydroxypropylcellulose), corn starch, iron oxide, lactose, magnesium stearate, polyethylene glycol, sodium starch glycolate, silicon dioxide, talc and titanium dioxide.

What dosage forms Femara comes in

FEMARA (letrozole) 2.5 mg tablets

FEMARA is supplied as film-coated tablets. The film-coated tablets are dark-yellow and round with bevelled edges. They are marked with “FV” on one side and “CG” on the other.

FEMARA is supplied in blister packs containing 30 tablets.

Warnings and Precautions

Serious Warnings and Precautions

FEMARA should be used under the supervision of a doctor experienced in the use of anti-cancer drugs.

FEMARA reduces blood estrogen levels which may cause a reduction in bone mineral density and a potential increase in bone loss (osteoporosis) and/or bone fractures.

The use of aromatase inhibitors, including FEMARA, may increase the risk of cardiovascular events compared to tamoxifen, such as heart attacks and stroke. Women at risk of heart disease should be carefully monitored by their doctor.

You should not use FEMARA if you may become pregnant, are pregnant and/or breastfeeding. There is a potential risk of harm to you and the fetus, including risk of fetal malformations. If you have the potential to become pregnant (this includes women who are perimenopausal or who recently became postmenopausal), you should discuss with your doctor about the need for effective contraception.

If there is exposure to FEMARA during pregnancy, you should contact your doctor immediately to discuss the potential of harm to your fetus and potential risk for loss of the pregnancy.

FEMARA should not be used in children and adolescents under 18 years of age.

Before you take FEMARA

Tell your doctor if you

  • have a serious kidney or serious liver disease;

  • are taking hormone replacement therapy;

  • are taking other medication to treat your cancer;

  • have a personal or family history of osteoporosis or have ever been diagnosed with low bone density or have a recent history of fractures (in order for your doctor to assess your bone health on a regular basis).

  • have a personal or family history of high blood cholesterol or lipid levels. FEMARA may increase lipid levels.

  • have or have had cardiovascular or heart disease including any of the following: heart attack, stroke or uncontrolled blood pressure. FEMARA may increase the risk of cardiovascular or heart diseases.

  • have an intolerance to milk sugar (lactose);

Driving a vehicle or using machinery

FEMARA tablets are unlikely to affect your ability to drive a car or to use machinery. However, some patients may occasionally feel tired, dizzy, sleepy or experience visual disorders. If this happens, you should not drive or operate any tools or machinery until you feel normal again.

Interactions with Femara

Please tell your doctor or pharmacist if you are taking or have recently taken any other prescription or over-the-counter medicines, vitamins or natural health products during your treatment with FEMARA.

Proper Use of Femara

Usual dose

The usual dosage is one tablet of FEMARA to be taken once daily. The tablet should be swallowed whole with a small glass of water. You can take FEMARA with or without food. It is best to take FEMARA at about the same time every day.


If overdosage is known or suspected, contact your doctor or the nearest poison control centre for advice immediately. Show the pack of tablets. Medical treatment may be necessary.

Technical Information