Plavix 75 mg

Generic Name: Clopidogrel 75 mg
Plavix 75 mg Image

Images for reference only. Packaging will vary.

Plavix Facts

The brand name medication PLAVIX is marketed by two companies, Bristol-Myers Squibb and Sanofi-Aventis.

PLAVIX is marketed in over 110 countries, with annual sales of over $6 billion dollars.

Over the last several years, PLAVIX has been rated as the second best selling drug in the world.

PLAVIX is the brand name of a medication containing the active ingredient clopidogrel, which is an antiplatelet agent.


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What is Plavix? General Information

Plavix is an oral anti platelet agent marketed by Bristol Meyers Squibb and Sanofi Aventis. Plavix is widely regarded as the number one anti platelet prescription drug available

Plavix is an oral anti platelet agent which is proven to prevent blood clots, heart attacks, and strokes. Blood clots are caused by platelets within blood sticking together, and are the cause of most heart attacks and strokes. Plavix helps to prevent these blood clots. Plavix has gone through 4 extremely large clinical trials where over 80,000 patients have been tested. The results have been a success and make Plavix the number one anti platelet prescription medicine. Plavix is recommended for individuals who have already suffered one clot related heart attack, chest pain, or for individuals diagnosed with Peripheral Artery Disease (commonly referred to as P.A.D).

Plavix is sometimes misspelled as: plavex, plevex

When should Plavix be taken?

Plavix is an anti platelet agent and is taken orally. Plavix comes in the form as a 75 milligram oral tablet. The amount of milligrams each patient should consume daily can vary from patient to patient, and is prescribed by the patient's doctor, but is generally to just one tablet per day. The level of the prescription will also depend on other medications being taken by the patient. Plavix should be taken around the same time everyday, as it is important for the patient to have a consistent schedule. Plavix can be taken with out without food, but consumption should always follow the prescribed schedule.

Side Effects

Many people who take Plavix don't experience any side effects. If you experience minor bleeding or easy bruising, you should check with your doctor to see if Plavix is right for you. If you experience any of the following side effects, seek medical attention immediately: allergic reactions (rash, itching, hives, difficulty breathing, etc.), change in vision, or bloodied eyes, chest pains, speech problems, persistent headaches, sore throat, fever, or unexplained weight loss. If you are experiencing any other side effect that you feel are due to Plavix, it is always a good idea to consult with a physician immediately or cut off use of Plavix.

Other Brand Names

Plavix medical name is Clopidogrel. Other brand names are as follows
Clopile - Offered by Ranbaxy Laboratories
Ceruvin / Clavix - Offered by Intas Pharmaceuticals

Safety Information:

Prior to taking Plavix, check with your physician if you have any of the following conditions: retinal hemorrhages, skull hemorrhaging, kidney ulcers or other serious kidney issues, severe liver disease, stomach or intestinal bleeding, or if you've had a recent operation or injury of any kind.

In November 2009, the FDA warned patients should not combine Plavix with Nexium, Prilosec, Prozac, or Tagamet. These drugs make Plavix significantly less effective. The warning came after a study performed by Sanofi Aventis proved that those drugs significantly reduce the effect of Plavix. The FDA also said drugs such as Zantac and Pepcid do not negatively impact Plavix.

Dosage:

Patients should take one 75 milligram tablet daily.

Visual Description:

A 75 milligram tablet of Plavix is a small circular tablet that is light pink in color. One side of the table has "75" ingrained into it. The other has four small lines which appear to heading into each other from opposite directions, but are stopped prior to connecting.

A Plavix package is rectangular shaped, is royal blue, and has large white lettering which says "Plavix," except the "I" is dotted with a red dot. Below "Plavix" it ways "75 mg film-coated table "Clopidogrel" in smaller white lettering.

About Plavix

What Plavix is used for

You have been prescribed PLAVIX because you are at risk for experiencing unwanted blood clots (thrombi). These blood clots can lead to symptoms which present in different manners, such as strokes, unstable angina, heart attacks, or peripheral arterial disease (leg pain on walking or at rest). PLAVIX is taken to prevent further blood clots from forming thereby reducing the risk of having unstable angina, a heart attack or another stroke.

This product has been prescribed for you personally and you should not pass it on to others.

What Plavix does

PLAVIX tablets belong to a group of medicines called antiplatelet drugs. Platelets are very small structures in blood, smaller than red or white blood cells, which clump together during blood clotting. By preventing this clumping, antiplatelet drugs reduce the chances of blood clots forming (a process called thrombosis).

When Plavix should not be used

  • If you are allergic to any of the substances contained in the tablets (see What the medicinal ingredient is: and What the important nonmedicinal ingredients are: ).

  • If you have a medical condition that is causing bleeding, such as a stomach ulcer.

  • If you have liver disease or damage.

What the medicinal ingredient is

Clopidogrel bisulfate.

What the important nonmedicinal ingredients for Plavix are:

Low substituted hydroxypropylcellulose, mannitol, microcrystalline cellulose, polyethylene glycol 6000 and hydrogenated castor oil. The pink film coating contains lactose, hypromellose, titanium dioxide, triacetin and red iron oxide. The tablets are polished with carnauba wax.

What dosage forms Plavix comes in

PLAVIX comes as 75 mg tablets. PLAVIX tablets are round, pink and engraved on one side with the number 75 and the number 1171 on the other side.


Warnings and Precautions

BEFORE you use PLAVIX talk to your doctor or pharmacist if:

  • You have had an allergic reaction to any of the substances contained in the tablets.

  • You have a medical condition that is causing bleeding, such as a stomach ulcer.

  • You are taking any other medications (such as acetylsalicylic acid (ASA), other drugs used to reduce blood clotting such as warfarin and heparin or Non-Steroidal Ant-Inflammatory Drugs [NSAIDs; drugs used to treat painful and/or inflammatory conditions of muscles or joints]), including those that you buy without a prescription.

  • You are pregnant or become pregnant on PLAVIX, or you are breast-feeding.

  • You have a recent serious injury.

  • You have liver disease or damage.

  • You have recently undergone surgery (including dental surgery).

  • You will be having surgery. Your doctor may ask you to stop taking PLAVIX for 5-7 days before your surgery.

  • You have a blood disorder that makes you prone to internal bleeding (bleeding inside any tissues, organs or joints of your body) or tend to bleed longer than 10 minutes without taking any drugs.

While you are on PLAVIX it is important that you do not take any medicine other than that prescribed by your doctor. If you should see another doctor or a dentist while you are using PLAVIX, you should inform them that you are using PLAVIX.


Interactions with Plavix

Drugs that may interact with PLAVIX include: ASA, NSAIDs, heparin, warfarin, digoxin, theophylline, antacids.


Proper Use of Plavix

Usual dose

Adults (including the elderly): You should take one 75 mg tablet of PLAVIX per day, by mouth. PLAVIX can be taken with or without food. You should take your medicine regularly and at the same time each day. If you have had unstable angina or a heart attack, a one-time 300 mg dose may be administered followed by one 75 mg tablet daily.

Children and Adolescents: PLAVIX is not recommended for children or adolescents below 18 years of age.

PLAVIX should be taken long term under supervision of your doctor.

Overdose

If you take an overdose of tablets inform your doctor at once or go to the nearest hospital emergency department. A large dose of tablets could put you at risk of serious bleeding, requiring emergency treatment.

Missed dose

If you forget to take a dose of PLAVIX, but remember within 12 hours of your usual time, take your tablet immediately and then take your next tablet at the normal time. If you forget for more than 12 hours simply take the next single dose at the usual time. Do not take a double dose to make up for the one you missed. You can check the day on which you last took a tablet of PLAVIX by referring to the calendar printed on the blister strip.


Side Effects for Plavix and What to Do About Them

Occasional side effects reported with PLAVIX are:

  • Rashes and/or itching

  • Diarrhea

  • Abdominal pain

  • Indigestion or heartburn

  • Constipation

  • Bleeding in the stomach, bowels or into the eye

  • Hepatic (liver) and biliary (bile) disorders

  • Blood in the urine (haematuria)

  • Generalized allergic reactions such as swelling of the face, lips and/or tongue, shortness of breath

  • Bleeding from blood vessels inside the head has been reported in a very small number of cases.

In very rare cases, joint pain and/or muscle pain are reported.

Contact immediately your doctor if you experience:

  • Fever, signs of infection or extreme tiredness. This may be due to rare decrease of some blood cells.

  • Signs of liver problems such as yellowing of the skin and/or eyes (jaundice), whether or not associated with bleeding and/or confusion.

If you notice any undesirable effects, especially during the first few weeks of treatment, including any not mentioned above, promptly notify your doctor for assessment and follow-up.

If you cut or injure yourself, it may take slightly longer than usual for bleeding to stop. This is linked to the way your medicine works. For minor cuts and injuries, e.g. cutting yourself shaving, this is of no concern. However, if you are in any doubt at all, you should contact your doctor immediately. Your ability to drive or operate complicated machinery should not be affected.

Serious Side Effects, How Often They Happen and What To Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Abdominal pain DiarrheaIndigestion    
Bruising Nose bleeds Bleeding in stomach, bowels    
Uncommon Fever, signs of infection, extreme tiredness, signs of liver problems   • (Immediately)  
Nausea Constipation Vomiting    
Bleeding in the eye    
Dizziness Headache Tingling sensation    
Rash Itching    

This is not a complete list of side effects. For any unexpected effects while taking PLAVIX, contact your doctor or pharmacist.


Technical Information

What Others Are Saying About plavix:

Jospeh Cowger on Friday September 12, 2008

Taking Plavix has been a reality for me for some time. Actually, I take the generic Clopidogrel to save money. I was tired of having to go down to the local pharmacy all the time. I liked my pharmacist, but I didn't like the driving, and waiting in line. When I order from the drug company, all of that pain goes away.

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