Agrylin 0.500 mg

Generic Name: Anagrelide 0.500 mg
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Best Value On Brand Agrylin 0.500 mg
Price: $8.67 per capsule!
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Agrylin 0.500 mg Prescription Required
100 capsules for $866.65 ($8.67 per capsule)
Agrylin from online pharmacy: the UK
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Best Value On Generic Anagrelide 0.500 mg
Price: $4.26 per capsule!
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Anagrelide 0.500 mg Prescription Required
100 capsules for $425.57 ($4.26 per capsule)
Anagrelide from online pharmacy: Canada
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Drugs in other countries are sometimes sold using different trade names which will appear on the packaging. This product is sold in other countries as:

  • Xagrid

Our licensed online pharmacy offers Agrylin 0.500 mg for sale. Enhance your life and manage your blood thinner with medications like Agrylin 0.500 mg. Your doctor should be consulted before taking any new medication. It is possible, in some cases, to obtain a generic version of a particular medication; e.g. a generic substitute for Agrylin 0.500 mg. The generic is therapeutically equivalent and often costs less, which means you can save money when buying your rx online from The Drug Company.

About Agrylin

What Agrylin is used for

Agrylin is prescribed for the treatment of patients with thrombocythemia secondary to myeloproliferative disorders. Thrombocythemia is a condition in which there are too many platelets (the little cells which help the blood to clot) in the blood. Myeloproliferative disorders are diseases in which one or more of the types of cells that make up the blood are being overproduced.

Lowering platelet counts results in improving symptoms, including serious symptoms related to blockages in blood vessels and bleeding.

Agrylin is intended for long-term usage and has not been evaluated for treatment of the short-term life threatening complications of having too many platelets in the blood.

What Agrylin does

The way that Agrylin works in the body to reduce your platelet count is not fully understood. Agrylin is believed to reduce the number of platelets by affecting megakaryocytes (the cells that produce platelets). Its action slows down platelet production.

Although Agrylin lowers platelet counts to more normal levels, it does not affect the body's natural process to clot blood when needed.

When Agrylin should not be used

You should not take AGRYLIN if you:

  • Have severe liver disease

  • Are allergic to anagrelide and other nonmedicinal ingredients (see What the important nonmedicinal ingredients are:).

What the medicinal ingredient is

Anagrelide hydrochloride.

What the important nonmedicinal ingredients for Agrylin are

Crospovidone, black iron oxide, gelatine, lactose anhydrous, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, silicone dioxide, sodium lauryl sulphate, titanium dioxide.

What dosage forms Agrylin comes in

Capsule 0.5 mg.


Warnings and Precautions

BEFORE you use Agrylin talk to your doctor or pharmacist if:

  • You have heart, liver or kidney disease

  • You are pregnant or planning a pregnancy

  • You are breast feeding

Agrylin is not recommended in women who are or may become pregnant.

Limited data are available in patients under the age of 16 years.

Caution should be used when driving vehicles or machinery.


Interactions with Agrylin

Tell your doctor or pharmacist about any medication that you are taking, including non-prescription medications and natural health products.

Drugs that may interact with Agrylin include:

  • acetylsalicylic acid,

  • fluvoxamine,

  • omeprazole,

  • theophylline,

  • milrinone,

  • CYP1A2 substrates/inhibitors.

The potential risks and benefits of concomitant use of anagrelide with acetylsalicylic acid should be assessed by your doctor, particularly in patients with a high risk profile for haemorrhage (bleeding), before starting treatment.

Grapefruit juice and sucralfate (a sweetener) may also interact with Agrylin. Food may slow down the rate at which Agrylin is absorbed into your body.


Proper Use of Agrylin

Usual dose

Take as directed by your doctor.

Your doctor may check for heart disease before starting you on Agrylin.

Regular blood tests will be done at the start of your treatment to ensure that Agrylin is working for you.

If you have kidney or liver problems, your doctor will monitor their function while you are taking Agrylin.

Overdose

Possible symptoms of an overdose of anagrelide could include low platelet count, which can potentially cause bleeding. In case of an overdose, please contact your doctor or go to the nearest hospital or emergency room.

Missed dose

If you miss a dose at the beginning of your treatment, contact your doctor or pharmacist.

If you miss a dose during your long-term treatment, take the missed dose as soon as possible, unless it is almost time for your next dose. Skip the missed dose if it is almost time for your next regular dose. Do not take two doses at the same time.


Side Effects for Agrylin and What to Do About Them

The most frequently reported adverse reactions to Agrylin in clinical trials were: headache, diarrhea, fatigue, swelling, nausea, abdominal pain, whirling sensation, pain, gas, vomiting, fever, redness and itching of skin, loss of appetite, sore throat, malaise, cough, tingling, back pain, digestive problems.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Very Common (reported by more than 10% of patients in clinical trials) Pounding or irregular heartbeat (palpitations)    
Swelling in your feet or ankles (edema)    
Trouble breathing or shortness of breath (dyspnea)    
Chest pain    
Common (reported by between 1% and 10% of patients in clinical trials) Swollen legs or ankles or difficulty breathing (common signs of heart disease or heart failure)    
Fast hearbeat (tachycardia)    
Trouble vision    
Blood in your stools or urine    
Bleeding    
Fever, cough, chest pain and shortness of breath (common signs of respiratory infection, pneumonia or bronchitis    
Difficulty breathing (asthma)    

This is not a complete list of side effects. For any unexpected effects while taking Agrylin, contact your doctor or pharmacist.

You may also experience

Chills, flu symptoms, infection, neck pain, flushing, low blood pressure (when standing or not), loss of consciousness, clot in a blood vessel, high blood pressure, constipation, difficulty swallowing, dry mouth, abnormal number of blood cells, bruises, muscle and bone pain, depression, somnolence, insomnia (difficulty falling asleep), confusion, nervousness, loss of memory, changes in weight, dehydration, nose bleeding, respiratory disease, infection of the sinuses, sweating, hair loss, skin problems, ear problems, irritation or infection of the eye, ringing in the ear, urinary problems, allergic coughing.

Call your physician immediately if you experience the following symptoms: shortness of breath and difficulty breathing, fluid buildup around the ankles, fast or irregular heartbeat, and chest pain.


Technical Information