Zestril Medication Information:

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Generic is available for less money: Generic Lisinopril

Zestril medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Zestril 2.500 mg
Zestril 5 mg
Zestril 10 mg
Zestril 20 mg

Zestril Information

Zestril is in the group of drugs known as ACE inhibitors. It is often used to treat high blood pressure (hypertension), congestive heart failure, and can be used after a heart attack to improve chances of survival.

How does Zestril Work

Zestril works by relaxing the blood vessels and helping the heart to pump blood that carries the oxygen to different parts of the body more efficiently. When these blood vessels relax, they widen and the overall effect is a drop in blood pressure. This reduced drop in blood pressure means the body doesn't have to work as hard when pumping blood. When used immediately after a heart attack, it can also significantly lower the risks of having another heart attack. It has also been approved, and is safe, for use in children 6 years and older. While Zestril does help in these conditions, it does not cure them, and the medication will need to be continued even after symptoms lessen.

How to take Zestril

Depending on the condition being treated, the usual dosage for Zestril ranges from 2.5mg to 40mg daily, and is taken once daily, with or without food. The dosage prescribed is influenced by weight, medical conditions, and other medications being taken. People taking other medications for high blood pressure take lower doses. Zestril should be taken regularly, but if a dosage is missed, you should take it as soon as possible. However, if it is almost time for your next dosage, you should just skip the dosage all together. It can take up for two weeks for results to be recognized.

Side Effects

There are some common side effects of this drug. Sometimes as the body gets used to the drug the side effects will go away on their own. Some of these side effects may include a dry, persistent cough, and headaches. Some of the less common side effects of Zestril are diarrhea, nausea, a loss of taste, and unusual tiredness. There are also some less common side effects sometimes seen, and your physician should be contacted if any of these arise. They include, fainting, skin rashes, abdominal pain, and chest pains. Medical attention should be immediately sought if any of the following occur, fever and chills, swelling of hands, face, mouth or feet, and sudden trouble swallowing or breathing.

Other Names for Zestril

  • Lisinopril
  • Prinivil

Safety Information:

The medication Zestril should not be taken if you have had a previous allergic reaction to it, or any of the other ACE inhibitors. If you have been diagnosed with idiopathic or hereditary angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness) you should also avoid taking this medication. People who have kidney disease, maintain high levels of potassium in their blood, or have diabetes may also in counter problems when taking Zestril, so a physician should be informed before you begin taking it. Zestril is classified as a pregnancy drug "D," so women who are pregnant or nursing should also avoid this drug.


Zestril Dosages Available

  • 2.5mg capsule
  • 5mg capsule
  • 10mg capsule
  • 20 mg capsule
  • 40 mg capsule

Visual Description:

When prescribed as Zestril the capsules are round or shield shaped, and can be found in pink, white, red, or yellow. They will have Zestril imprinted on one side.

Zestril Facts

Zestril is manufactured by IPR Pharmaceuticals, Inc, for AstraZeneca Pharmaceuticals LP.

How well patients tolerate Zestril therapy was evaluated in controlled clinical trials.

Clinical trials evaluated Zestril treatment in 1,969 patients diagnosed with hypertension or heart failure.

Zestril obtained original or tentative approval from the FDA on May 19, 1988.


Technical Information