Coversyl Medication Information:

Price Break On Coversyl
Generic is available for less money: Generic Perindopril

Coversyl medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Coversyl 2 mg
Coversyl 4 mg
Coversyl Plus 4mg/1.25mg
Coversyl 8 mg

About Coversyl

What Coversyl is used for

Your doctor has prescribed COVERSYL to treat your mild to moderate hypertension. Hypertension is the medical term for high blood pressure.

You may be prescribed COVERSYL to treat mild to moderate congestive heart failure along with other medications.

COVERSYL is also indicated for the reduction of cardiovascular risk in patients with hypertension and/or those who have suffered a heart attack.

What Coversyl does

COVERSYL belongs to a class of medicines called ACE inhibitors. These work by widening the blood vessels, which makes it easier for your heart to pump blood through them.

When blood pressure flows through the blood vessels it pushes against their walls. This pressure helps get your blood all around the body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have high blood pressure when your blood pressure stays higher than is needed, even when you are calm or relaxed.

There are usually no symptoms of high blood pressure. When blood pressure is high, damage can occur to the heart and blood vessels. The only way of knowing that you have high blood pressure is to have your blood pressure checked on a regular basis.

Heart failure means that the heart muscle cannot pump blood strongly enough to supply all the blood needed throughout the body. Heart failure may start off with no symptoms, but as the condition progresses, you may feel short of breath or may get tired easily after light physical activity such as walking. You may wake up short of breath at night.

When Coversyl should not be used

Do not take COVERSYL if:

  • you have experienced swelling of the face, tongue, lips or throat either spontaneously or in response to another medicine of the same family in the past (this rare condition is known as angioedema),

  • you are allergic to the active substance or any of the other ingredients of COVERSYL (see What the important nonmedicinal ingredients are:).

Coversyl is not intended for use in children and adolescents (under 18 years old).

What the medicinal ingredient is

The active substance of COVERSYL is perindopril erbumine.

What the important nonmedicinal ingredients for Coversyl are

The nonmedicinal ingredients in the COVERSYL tablet are: microcrystalline cellulose, lactose monohydrate, hydrophobic colloidal silica, and magnesium stearate. The 4 and 8 mg tablets also contain chlorophyllin (E141ii) aluminium lake as a colorant.

What dosage forms Coversyl comes in

COVERSYL comes in tablets of 2 mg, 4 mg or 8 mg.

Warnings and Precautions

Serious Warnings and Precautions

COVERSYL should not be used during pregnancy. If you discover that you are pregnant while taking COVERSYL, stop the medication and please contact your physician as soon as possible.

BEFORE you use COVERSYL talk to your doctor or pharmacist if:

  • You perform tasks which may require special attention (for example driving an automobile or operating dangerous machinery).

  • you suffer from kidney or liver disease,

  • you undergo surgery,

  • you are taking diuretics (drug used to treat high blood pressure),

  • you are taking vasodilators including nitrates (products that make the blood vessels become wider),

  • you are taking, have recently taken or intend to take any other medicines, even those not prescribed,

  • you have a heart condition,

  • you undergo dialysis,

  • you have diabetes,

  • you have systemic lupus erythematosus (SLE),

  • you have a skin condition known as “hard skin” (thickening of the skin),

  • you are on a salt-restricted diet,

  • you are suffering from severe diarrhea or vomiting,

  • you have recently or are planning to get allergy shots for bee or wasp stings.

Be aware that excessive perspiration, dehydration and conditions such as diarrhea and vomiting can cause a drop in blood pressure and this may aggravate the side effects of COVERSYL, so consult your doctor when this occurs.

Taking COVERSYL during pregnancy can cause injury and even death to your baby. This medicine should not be used during pregnancy. If you become pregnant while taking COVERSYL, stop the medication and report to your doctor as soon as possible. It is possible that COVERSYL passes into breast milk. You should not breast-feed while taking COVERSYL.

Interactions with Coversyl

Before you take COVERSYL, talk to your doctor if you are undergoing kidney dialysis using polyacrylonitrile membranes.

Drugs that may interact with COVERSYL, and that you should not be taking without the advice of your doctor, include:

  • diuretics (“water tablets”)

  • lithium tablets

  • potassium supplements or potassium containing medicine,

  • insulin or oral hypoglycemics,

  • allopurinol,

  • procainamide,

  • non-steroidal anti-inflammatory drugs (NSAIDs),

  • dextran sulphate,

  • other medications for high blood pressure (e.g. nitroglycerin, nitrates),

  • digoxin,

  • gentamicin,

  • tricyclic antidepressants,

  • anaesthetics,

  • medications for mental disorders,

  • treatment for bee and wasp allergies.

Proper Use of Coversyl

Usual dose

Always follow your doctor's instructions about how to take COVERSYL. You should check with your doctor or pharmacist if you are not sure.

The recommended dose of COVERSYL to treat hypertension is one 4 mg-tablet taken in the morning. In some cases, as prescribed by your doctor, the dose could be doubled to 8 mg taken in the morning in a single daily dose.

The recommended dose of COVERSYL to treat heart failure is one 2 mg-tablet taken in the morning. In most cases, as prescribed by your doctor, the dose may be doubled to 4 mg taken in the morning in a single daily dose.

The recommended dose of COVERSYL when used to reduce the risk of cardiovascular risk in patients with hypertension and/or those who have suffered a heart attack is one 4 mg-tablet taken in the morning for 2 weeks. If the dose is tolerated, and as prescribed by your doctor, the dose should be increased to the maintenance dose of 8 mg per day taken in the morning. In older patients, the starting dose should be 2 mg once a day for the first week, followed by 4 mg once a day the second week and 8 mg once a day thereafter if tolerated.

Dosage should be adjusted at intervals of at least 2 to 4 weeks.

Do not stop taking your medicine without the advice of your doctor even if you feel better. If you stop, serious complications of the disease may occur.

COVERSYL is for oral use. Tablets should be swallowed whole with a glass of water, preferably in the morning before a meal. Your doctor will monitor your progress with COVERSYL and may perform occasional blood tests to ensure your continued health and safety.


If you suspect that you or someone else has taken more than the amount of COVERSYL prescribed by your doctor, contact your doctor immediately.

Missed dose

Do not take a double dose to make up for forgotten doses. Just carry on with the next dose at the usual time.

Side Effects for Coversyl and What to Do About Them

Like all medicines, COVERSYL can have side effects.

Most side effects are mild or moderate and usually transient. The most common side effects reported with COVERSYL are: cough (often described as dry and irritating, usually is worse at night or when lying down), headache, feeling weak. Other potential side effects are loss of taste or metallic taste in your mouth, rash. If you faint, discontinue the drug and contact your doctor.

Contact your doctor if these symptoms persist or get worse.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Common Feeling tired or lethargic    
Uncommon Angioedema (including swelling of the face, lips, tongue, throat, difficulties in breathing or swallowing. This is known to occur more frequently in black patients).    
Liver problems (symptoms of abdominal pain, nausea, vomiting, loss of appetite, jaundice (yellowing of eyes and skin).    
Infection (any signs of infection may be signs of a blood disorder).    
Allergic reactions (viral-like symptoms such as fever, lack of energy, muscle pain, rash).    
Irregular heart rate or chest pains.    
Difficulty in breathing, severe coughing.    
Severe abdominal pain with or without nausea or vomiting.    
Rash, sun sensitivity, other unusual skin irritation.    

This is not a complete list of side effects. For any unexpected effects while taking COVERSYL, contact your doctor or pharmacist.


Technical Information