Avapro

Avapro Medication Information:

Price Break On Avapro
Generic is available for less money: Generic Irbesartan

Avapro medication comes in several different strengths; click on the strength you need to view prices from pharmacies competing to earn your business.

Avapro 75 mg
Avapro 150 mg
Avapro 300 mg

What is Avapro

Avapro (also known as irbesartan) is a drug that inhibits blood vessels from narrowing, to lower blood pressure and to maintain healthy blood flow. It is in a group of drugs called angiotensin II receptor antagonists.

How does Avapro Work

Avapro works by decreasing the levels of specific chemicals in the body. It is used to lower blood pressure, kidney problems caused by type II diabetes. These are the main uses for Avapro but it is sometimes utilized to treat various issues other than what has been mentioned. Avapro inhibits the production of angiotensin II which constricts blood vessels. When Avapro is taken and it stops the production of angiotensin II, resulting in relaxed blood vessels and decreased blood pressure. It takes about 4 weeks for apparent results take place. Oftentimes, Avapro is used in combination with other medications.

How is Avapro Taken

Avapro should only be taken as prescribed. It can be taken with food or without and requires monitoring blood pressure regularly. It is important to continue the usage of this medication even if symptoms go away. Avapro/ irbesartan is usually prescribed at 150 mg per day and should be taken at the same time each day. The doctor may increase the dosage to 300 mg if blood pressure does not reduce. If a dose is missed, it should be taken as soon as possible but if it is more than 12 hours after your usual dose then skip the missed dose and go back to the regular schedule.

Side Effects

At least 1% of people taking Avapro report side effects. Most of these side effects can be managed and/or may disappear over time.

  • Anxiety/Nervousness
  • Belching/Heartburn
  • Cold-like Symptoms
  • Diarrhea
  • Headache
  • Muscle/Bone Pain
  • Tiredness

The following is a list of rare side effects.

  • Difficulty breathing/swallowing
  • Dizziness/light headedness/fainting
  • Hoarseness
  • Swelling of face, feet, hands, lips, tongue
  • Tightening of the throat

All medications have side effects. Side effects can be mild or severe, temporary or permanent. It is important to notify the doctor of anything out of the ordinary and to pay close attention to bodily reactions to this medication. This medication may cause drowsiness, kidney problems, liver problems, or low blood pressure. It is very important to notify the doctor of any of the following health conditions exist:

  • Heart disease
  • Recent heart attack or stroke
  • Valvular stenosis
  • Pregnancy
  • Breast-feeding

Safety Information:

Avapro/irbesartan should not be taken by anyone who may have allergies to any of the ingredients or by anyone who is pregnant. Avapro may interact with some other medications such as diuretics, lithium, medications that increase potassium in the blood, other blood pressure medications, or potassium supplements and/or pills.

Dosage:

  • 75 mg - Each tablet contains 75 mg of irbesartan.
  • 150 mg - Each tablet contains 150 mg of irbesartan
  • 300 mg- Each tablet contains 300 mg of irbesartan

Visual Description:

Each tablet is white to off white biconvex, oval shaped with a heart shape embossed on one side. On the other side, each has a different code on it. 300 mg has the numbers "2773", 150 mg has "2772" and the 75 mg has "2771".

Why has my physician prescribed Avapro?

Your physician has prescribed Avapro because you have a condition known as hypertension or high blood pressure. Your physician may have also prescribed Avapro if you have high blood pressure and type 2 diabetes mellitus to protect your kidney function.


What is blood pressure?

Blood pressure is the force of blood against the walls of your arteries (blood vessels that carry blood away from the heart). You need some blood pressure for the blood to circulate through your body. If the blood pressure gets too high, it is called high blood pressure or hypertension.

Your blood pressure changes during the day depending on activity, stress and excitement.


How is blood pressure measured?

Blood pressure is measured in millimeters of mercury (mmHg) and is recorded as 2 numbers, for instance 120/80 (read as 120 over 80). The upper number is the systolic pressure and the lower number is the diastolic pressure.

The systolic pressure is the pressure in the arteries when the heart beats. The diastolic pressure is the pressure in the arteries when the heart relaxes between beats.


What is high blood pressure or hypertension?

You have high blood pressure or hypertension if your blood pressure is persistently higher than the normal limits, even when calm or relaxed.


How do I know if I have high blood pressure?

There are usually no symptoms of high blood pressure. The only way of knowing that you have hypertension is to know your blood pressure. For that reason, you should have your blood pressure checked on a regular basis.


Why should high blood pressure be treated?

Left untreated, high blood pressure can damage vital organs like the heart and kidneys. You may feel fine and have no symptoms, but eventually hypertension can lead to strokes, heart attacks, heart failure, kidney failure or blindness.


What is kidney disease in patients with hypertension and type 2 diabetes mellitus?

When the kidneys deteriorate, they allow protein to pass in the urine. Early kidney disease is measured by detection of protein in the urine [microalbuminuria (MAU)] while more advanced stages are measured by increased levels of protein in urine (proteinuria). The presence of an abnormal protein level in the urine is a major risk factor for the progression of kidney disease (e.g. initiation of dialysis, kidney transplant) and heart disease.


How does Avapro treat high blood pressure?

Avapro lowers blood pressure by specifically blocking a natural substance called angiotensin II, which normally narrows your blood vessels. Treatment with Avapro allows the blood vessels to relax. Although your physician will be able to tell you that the medicine is working by measuring your blood pressure, you will probably feel no different while you are taking Avapro.

If your blood pressure remains too high after an adequate trial period, your physician may decide to increase the dose of Avapro. Avapro reduces blood pressure further when the dose is increased. This may avoid the need for an additional medication to control your blood pressure.


If I have hypertension and Type 2 diabetes, how can Avapro treat my condition?

In addition to controlling and lowering your blood pressure, recent studies have shown that Avapro protects your kidneys by reducing protein in the urine. This in turn slows the progression of your kidney disease.


Who should not take Avapro?

Do not take Avapro if:

  • You are pregnant, breast-feeding or thinking of becoming pregnant.

    Taking Avapro during pregnancy can cause injury and even death to your baby. This medicine should not be used during pregnancy. If you are planning to become pregnant while taking Avapro, contact immediately your doctor.

    It is possible that Avapro passes into breast milk. You should discuss with your doctor about taking Avapro while breast-feeding.

  • If you are allergic to any of the ingredients.

Avapro should not be given to children.

If any of the above apply to you, inform your doctor or pharmacist first and ask for their advice.


Other important information before taking Avapro

There are certain conditions which you may have, or have had, which require special care before or while taking Avapro. Therefore, before taking this medicine, you should tell your doctor if you think any of the following applies to you:

  1. You suffer from low blood pressure;

  2. You are taking a “water pill”;

  3. You are vomiting or have severe diarrhea;

  4. You are on a particular diet—low on salt;

  5. You are on dialysis;

  6. You have kidney problems.

If you are to undergo any surgery or receive anesthetics, you should make sure your doctor knows that you are taking Avapro.


Can I take Avapro with other medications?

Tell your doctor if you are taking other medications.

Do not take any other medications, including over-the-counter products, unless you have discussed the matter with your doctor. Certain medications tend to increase your blood pressure, for example, preparations for appetite control, asthma, colds, coughs, hay fever and sinus problems.


Can I drive or operate machinery while using Avapro?

Almost all patients can, but you should not perform tasks which may require special attention (for example, driving an automobile or operating dangerous machinery) until you know how you respond to your medicine.


How should I take Avapro?

Take Avapro every day exactly as your physician has instructed. It is important to continue taking Avapro for as long as your physician prescribes it in order to maintain control of your blood pressure.

Avapro may be taken with or without food.


What should I do if I miss a dose?

Try to take Avapro daily as prescribed. If you miss a dose, do not take an extra dose. Just resume your normal schedule.


What should I do in case of an overdose?

Contact your physician immediately so that medical attention can be given promptly.


What undesirable effects may Avapro have?

Along with its intended action, any medication, including Avapro, may cause side effects. Most patients do not have side effects from taking Avapro, but if you notice any of the following or any other unusual symptoms tell your pharmacist or your doctor right away:

  • Dizziness

  • Lightheadedness

  • Rash

  • Being tired

  • Diarrhea

  • Muscle pain

Side effects such as myalgia (muscle pain), myasthenia (muscle weakness), myositis (muscle inflammation) and rhabdomyolysis (a muscle-wasting disease), in rare cases leading to kidney failure, have been reported with the use of angiotensin II receptor blockers, the class of drugs to which Avapro belongs. You should contact your physician promptly if you experience muscle pain that you cannot explain, muscle tenderness or weakness, generalized weakness, or when you notice dark/brown urine.


Avapro Facts

Avapro belongs to a relatively new family of drugs called angiotensin II receptor antagonists.

Avapro was Bristol-Myers Squibb's third best-selling product in 2008.

Irbesartan, the generic name of Avapro, was developed by Sanofi Research and today is marketed jointly by Sanofi and Bristol-Myers Squibb.

In 1858, the pharmaceutical laboratory that would become Bristol-Myers Squibb was founded by Dr. Edward Squibb in Brooklyn, New York.

 

Technical Information

What Others Are Saying About avapro:

Tonya S. Seals on Thursday April 16, 2009

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