Viracept 250 mg

 
Viracept 250 mg Image

Images for reference only. Packaging will vary.


Ask A Pharmacist

Please feel free to ask our pharmacists any questions about Viracept.

Click Here To Ask A Question

Best Value On Brand Viracept 250 mg
Price: $3.72 per tab!
In Stock
Viracept 250 mg Prescription Required
300 tabs for $1,116.23 ($3.72 per tab)
Viracept from online pharmacy: Canada
Guaranteed US Delivery

After ordering your Viracept 250 mg online, you will want to tell your friends about The Drug Company. The convenience you experience, and the money you save will be remarkable. A cheap generic alternative for aids may be available from our licensed pharmacies. While many products require a prescription, sometimes no prescription is necessary. Those are known as over-the-counter (OTC) products and can be purchased without a prescription. Our pharmacy network can help you save money. Order with confidence from Canada, New Zealand, Great Britain and many others, and enjoy our no hassle 90 day return policy.

About Viracept

What Viracept is used for

VIRACEPT is the brand name of the antiviral agent, nelfinavir mesylate. It is a member of a class of drugs called protease inhibitors. VIRACEPT is an important part of your anti-HIV therapy. It is active against the Human Immunodeficiency Virus (HIV), helping to reduce the number of HIV particles in blood.

Your doctor has prescribed VIRACEPT for you because you have HIV infection. HIV infection is a disease spread by contact with blood or sexual contact with an infected person.

VIRACEPT should be taken in combination with other antiretroviral agents. This combination has been shown to reduce significantly the number of HIV particles in the blood and to increase significantly circulating CD4 cells.

This product has been prescribed for you personally, and you should not pass it on to others.

VIRACEPT is not a cure for HIV infection or AIDS. People taking VIRACEPT may still develop opportunistic infections or other illnesses associated with HIV disease. Some of these conditions are pneumonia, herpes virus infections, M. avium complex (MAC) infections, and Kaposi's sarcoma. You should, therefore, remain under the care of your doctor while taking VIRACEPT.

Treatment with VIRACEPT has not been shown to reduce the risk of transmission of HIV to others through sexual contact or blood contamination. Continue to practice safer sex and do not reuse or share needles. Even when you are on the anti-HIV medications and your HIV viral load is “undetectable”, you still have HIV in your body and you can still pass HIV to others. It is very important to take precautions to avoid passing HIV to others.

What Viracept does

VIRACEPT is a medicine which interferes with the action of an HIV protease enzyme, to prevent normal viral protein formation. This interference creates immature, non-infectious viral particles which helps reduce the infection.

When Viracept should not be used

  • If you are allergic or hypersensitive to nelfinavir or any of the components in the product (see What the important nonmedicinal ingredients are:)

  • If you are taking one or more of the following drugs:

    Drug class Drugs
    Gastrointestinal prokinetic cisapridea
    Antiarrythmics amiodarone, quinidine
    Ergot derivatives dihydroergotamine, ergonovine, ergotamine, methylergonovine
    Neuroleptic pimozide
    Sedative/hypnotics midazolam, triazolam
    HMG-CoA reductase inhibitors lovastatin, simvastatin
    a. is no longer marketed in Canada.

What the medicinal ingredient is

Nelfinavir mesylate.

What the important nonmedicinal ingredients for Viracept are

Crospovidone. Other nonmedicinal ingredients present in VIRACEPT film-coated tablets include calcium silicate, magnesium stearate, hypromellose and triacetin. In addition the 625 mg tablet contains colloidal silicon dioxide and the 250 mg tablet contains FD&C blue #2 powder.

Other nonmedicinal ingredients present in VIRACEPT oral powder{*not commercially available in Canada} include microcrystalline cellulose, maltodextrin, dibasic potassium phosphate, hydroxypropyl methylcellulose, aspartame, sucrose palmitate, and natural and artificial flavour.

What dosage forms Viracept comes in

Film-coated Tablets: 250 mg and 625 mg nelfinavir (from nelfinavir mesylate).

Oral Powder: 50 mg/g nelfinavir (from nelfinavir mesylate)*


Warnings and Precautions

Tell your health care provider before taking VIRACEPT if:

  • you have any medical problems, including liver disease, bleeding problems (hemophilia), or diabetes

  • You are taking any medications including nonprescription, herbal or street drugs, natural health products as many drugs may interfere with the action of VIRACEPT, or VIRACEPT may interfere with these other drugs. (See Interactions with This Medication:)

  • You are pregnant or planning to become pregnant. VIRACEPT not recommended for use in pregnant women.

  • You are breastfeeding or planning to breastfeed. There is a possibility that VIRACEPT may be excreted in breast milk. It is recommended that HIV-infected women not breastfeed their infants under any circumstances to avoid transmission of HIV. You should discuss with your doctor the best way to feed your baby.

Other warnings:

  • VIRACEPT may reduce the effectiveness of birth control pills, so an alternative or additional contraceptive measure should be used.

  • If you take sildenafil or other PDE-5 inhibitors and VIRACEPT together, you may be at increased risk of side effects such as low blood pressure, visual changes, and penile erection lasting more than 4 hours. If you suffer these side effects, seek immediate medical assistance.

  • Do not take St. John's Wort (Hypericum perforatum) (see Interactions with This Medication:)

  • The activity of VIRACEPT in children below the age of 2 is not yet known and should not be used in this group unless the doctor decides it is needed.

As VIRACEPT has not been shown to reduce the risk of transmission of HIV to others through sexual contact, practicing safer sex, such as using condoms is very important.

Talk to your doctor before you start taking any new prescription or non-prescription medicines or herbal supplements with VIRACEPT.


Interactions with Viracept

The following medications may interfere with the action of VIRACEPT, or VIRACEPT may interfere with the actions of these other medications. Your doctor will advise you whether these should be used or whether dosage adjustments may be necessary for VIRACEPT or these other drugs:

  • Cholesterol lowering medicines: VIRACEPT should not be taken with simvastatin and lovastatin (see When it should not be used:) and there is also a risk with atorvastatin and fluvastatin

  • carbamazepine, phenobarbital, phenytoin, rifampin, dexamethasone, calcium channel blockers

  • indinavir, ritonavir, saquinavir, rifabutin, delavirdine, omeprazole, fluticasone propionate, trazodone

  • sildenafil or other PDE-5 inhibitors. Your doctor will discuss with you the possible side effects of using both VIRACEPT and PDE-5 inhibitors together (see Other warnings)

  • St. John's Wort (Hypericum perforatum) may decrease VIRACEPT levels and lead to increased infection (viral load)


Proper Use of Viracept

Usual dose

Take VIRACEPT exactly as prescribed by your doctor. Do not increase or decrease the number of pills or doses per day or stop taking your anti-HIV medicines before speaking with your doctor, even if you are feeling better.

The following statements apply to VIRACEPT unless otherwise prescribed by your physician. Please observe these instructions for use, otherwise you will not fully benefit from VIRACEPT!

The recommended adult dose of VIRACEPT is 1250 mg given as five 250 mg tablets or two 625 mg tablets taken two times a day or 750 mg given as three 250 mg tablets to be taken three times a day, as prescribed by your physician. VIRACEPT tablets should be taken by mouth with a meal to help achieve higher VIRACEPT levels.

The usual dose of VIRACEPT oral powder* or tablets for children 2 to 13 years of age is 25-30 mg per kg three times daily as shown below. VIRACEPT oral powder and tablets should be taken by mouth, with a meal. The maximum recommended dose is 2500 mg per day. For children able to take tablets, VIRACEPT tablets may be administered instead of the oral powder.

Table 1: VIRACEPT Children Dose to be Administered Three Times Daily
Body Weight Number of Level 1 g Scoopsa Number of Level Teaspoonsb Number of 250 mg Tablets
Kg Lbs
7 to <8.5 15.5 to 18.5 4 1
8.5 to <10.5 18.5 to <23 5 1
10.5 to <12 23 to <26.5 6
12 to <14 26.5 to <31 7
14 to <16 31 to <35 8 2
16 to <18 35 to <39.5 9
18 to <23 39.5 to <50.5 10 2
≥23 ≥50.5 15 3
a. 1 level scoop contains 50 mg of VIRACEPT. b. 1 level teaspoon contains 200 mg of VIRACEPT.

Special considerations when taking VIRACEPT

Tablets

VIRACEPT Tablets are film-coated to help make them easier to swallow. If you are unable to swallow the tablets, they may be placed whole or crushed in a small amount of water to disperse before swallowing. They may also be crushed and mixed with a small amount of food. Once dispersed in water or mixed with food, the entire contents must be consumed. You should rinse your glass or dish with water and consume the rinse to ensure you have consumed your entire dose. Acidic food or juice (i.e., orange juice, apple juice or apple sauce) should not be used because it may result in a bitter taste.

Oral Powder*:

VIRACEPT oral powder may be mixed with a small amount of water, milk, formula, soy formula, soy milk, or nutritional preparations; once mixed, the entire contents must be consumed in order to obtain the full dose. It is recommended that VIRACEPT oral powder mixed in these media be consumed immediately. If it is not consumed immediately, the mixture must be stored under refrigeration (2-8ºC) for up to 6 hours. VIRACEPT oral powder should not be mixed with orange juice, apple juice, apple sauce or other liquids or foods that are acidic because the combination may result in a bitter taste. VIRACEPT Oral Powder should not be reconstituted with water in its original container.

How to optimize your use of VIRACEPT

VIRACEPT should be taken in combination with other antiretroviral agents. Clinical trials have found that combination antiviral therapy is more effective than one drug alone at reducing the amount of HIV in the blood and at reducing the development of resistance.

If you are taking both didanosine and VIRACEPT you should take VIRACEPT with a meal one hour after or more than two hours before you take didanosine.

Missed dose

It is very important that you take your VIRACEPT and other antiretroviral therapy every dose as prescribed by your doctor. If you miss a dose you should take the next dose as soon as possible. However, if you skip a dose, do not double the next dose. You should contact your doctor or pharmacist if you are unsure what to do.


Side Effects for Viracept and What to Do About Them

If you notice any unwanted effects not mentioned in this leaflet or if you are unsure about the effect of this product, please consult your doctor or pharmacist.

Any drug may have unintended or undesirable effects, so-called side effects. VIRACEPT has been shown to be generally well tolerated. Side effects include diarrhea, flatulence, nausea, rash, weakness, decreased white blood cell counts and increased values for liver enzyme and kidney function tests. The side effects observed in children and adults receiving VIRACEPT are similar. Some children experienced low white blood cells (leukopenia/neutropenia), which resolved without treatment interruption in most cases.

Diarrhea is the most common side effect in people taking VIRACEPT. In clinical studies, about 15-20% of patients receiving VIRACEPT 750 mg (three 250 mg tablets) three times daily or 1250 mg (five 250 mg tablets or two 625 mg tablets) two times daily had four or more loose stools a day. Diarrhea may be more common in patients receiving the 625 mg formulation. In most cases your doctor may advise you on the appropriate treatment for diarrhea caused by the medication and may include antidiarrheal medications such as loperamide or other approved agents.

Other side effects may occur with VIRACEPT. Ask your doctor or pharmacist for more information about side effects. Your doctor and pharmacist will have a more complete list of side effects. Inform your doctor promptly about these or any other unusual symptoms. If the condition persists or worsens, seek medical attention. Your doctor or pharmacist may be able to help you manage these side effects.

Serious Side Effects, How Often They Happen and What to Do About Them
Symptom/Effect Talk with your doctor or pharmacist Stop taking drug and call your doctor or pharmacist
Only if severe In all cases
Uncommon Allergic reaction with symptoms such as swollen mouth, throat, skin, difficulty in breathing or rash    
Low white blood cell count (leukopenia, neutropenia) with symptoms such as severe fatigue, infection or fever    
Rare New or worsening diabetes with high blood sugar that is sometimes severe, with symptoms such as frequent urination or increased thirst may occur    
Specifically for hemophiliacs (type A and type B). If nosebleed, bleeding gums, unexplained bruising, or dark urine and stools    

New onset diabetes mellitus, high blood sugar or an increase in severity of existing diabetes mellitus has been reported in patients receiving some protease inhibitors. In some of the cases high blood sugar was severe and some of the cases also associated with ketoacidosis.

In patients with hemophilia type A and B, there have been reports of increased bleeding while taking this treatment or another protease inhibitor. Should this happen to you, seek immediate advice from your doctor.

Changes in body fat have been seen in some patients taking antiretroviral agents. These changes may include increased amount of fat in the upper back and neck (“buffalo hump”), breast, and around the trunk. Loss of fat from the legs, arms and face may also happen. The cause and long-term health effects of these conditions are not known at this time.

VIRACEPT is mainly metabolized by the liver. The effects of VIRACEPT in patients with liver disease is unknown, therefore if you have liver disease it is very important that you alert your physician to any side-effects you have while taking VIRACEPT.

Make sure you tell your doctor or pharmacist of any medical problems that you may have, related or unrelated to HIV, before you start taking or while taking VIRACEPT. If, in any emergency situation, you are seeing a doctor other than your regular physician, make sure you tell them all the drugs that you are taking, including VIRACEPT.


Technical Information